UniProt P53135
DNA replication regulator SLD3 (P53135)
DNA replication regulator SLD3 (UniProt P53135): 3 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 34 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P53135
- Protein
- DNA replication regulator SLD3
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 34 · 3 records with a druggable one
Structures
4 records of P53135 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3WI3 | Crystal Structure of the Sld3/Treslin domain from yeast Sld3 | x-ray diffraction | A, B, C | SO4 | 9 (best 0.67) |
| 3WI3 | Crystal structure of the SLD3/TRESLIN domain from yeast SLD3 | x-ray diffraction | A, B, C | SO4 | 9 (best 0.67) |
| 8J09 | Crystal structure of the Sld3 Cdc45-binding-domain, in complex with Cdc45 | x-ray diffraction | A | — | 9 (best 0.88) |
| P53135 | AlphaFold monomer V2.0 prediction for DNA replication regulator SLD3 (P53135) | predicted | A | — | 7 (best 0.49) |
Ligands
- SO4 · Sulfate ion · in 2 records
Experiment against prediction
- 3WI3 chain A against the predicted model P53135: TM-score 1.00, RMSD 0.31 Å
- 3WI3 chain A against the predicted model P53135: TM-score 1.00, RMSD 0.31 Å
- 3WI3 chain C against the predicted model P53135: TM-score 0.98, RMSD 0.80 Å
- 3WI3 chain C against the predicted model P53135: TM-score 0.98, RMSD 0.80 Å
- 3WI3 chain B against the predicted model P53135: TM-score 0.98, RMSD 0.97 Å
- 3WI3 chain B against the predicted model P53135: TM-score 0.98, RMSD 0.97 Å
- 8J09 chain A against the predicted model P53135: TM-score 0.94, RMSD 2.10 Å
Elsewhere
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