UniProt P53115
Chromatin-remodeling ATPase INO80 (P53115)
Chromatin-remodeling ATPase INO80 (UniProt P53115), EC 3.6.4.-: 4 experimental structures and 1 predicted model on GenesisL1, 17 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P53115
- Protein
- Chromatin-remodeling ATPase INO80
- EC
- 3.6.4.-
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 17 · 2 records with a druggable one
Structures
5 records of P53115 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5NBN | Crystal structure of the Arp4-N-actin-Arp8-Ino80HSA module of INO80 | x-ray diffraction | G, H | — | — |
| 5NBN | Crystal structure of the ARP4-N-actin-ARP8-INO80HSA module of INO80 | x-ray diffraction | G, H | — | — |
| 8A5A | Structure of Arp4-Ies4-N-actin-Arp8-Ino80HSA subcomplex (A-module) of INO80 | electron microscopy | G | — | 7 (best 0.87) |
| 8ETU | Class2 of the INO80-Hexasome complex | electron microscopy | Q | — | 10 (best 0.86) |
| P53115 | AlphaFold monomer V2.0 prediction for chromatin-remodeling ATPase INO80 (P53115) | predicted | A | — | — |
Experiment against prediction
- 8ETU chain Q against the predicted model P53115: TM-score 0.73, RMSD 4.69 Å
- 5NBN chain G against the predicted model P53115: TM-score 0.54, RMSD 2.73 Å
- 5NBN chain G against the predicted model P53115: TM-score 0.54, RMSD 2.73 Å
- 8A5A chain G against the predicted model P53115: TM-score 0.48, RMSD 2.91 Å
Elsewhere
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