UniProt P53114
Mediator of RNA polymerase II transcription subunit 5 (P53114)
Mediator of RNA polymerase II transcription subunit 5 (UniProt P53114): 4 experimental structures and 1 predicted model on GenesisL1, 44 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P53114
- Protein
- Mediator of RNA polymerase II transcription subunit 5
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 44 · 5 records with a druggable one
Structures
5 records of P53114 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7UIC | Mediator-PIC Early (Tail A) | electron microscopy | e | — | 8 (best 0.86) |
| 7UIK | Mediator-PIC Early (Tail A + Upstream DNA & Activator) | electron microscopy | e | — | 9 (best 0.84) |
| 7UIL | Mediator-PIC Early (Tail A/B Dimer) | electron microscopy | e, 3 | — | 8 (best 0.85) |
| 7UIO | Mediator-PIC Early (Composite Model) | electron microscopy | Ae, Be | — | 3 (best 0.86) |
| P53114 | AlphaFold monomer V2.0 prediction for mediator of RNA polymerase II transcription subunit 5 (P53114) | predicted | A | — | 16 (best 0.74) |
Experiment against prediction
- 7UIK chain e against the predicted model P53114: TM-score 0.97, RMSD 1.69 Å
- 7UIO chain Ae against the predicted model P53114: TM-score 0.97, RMSD 1.69 Å
- 7UIL chain e against the predicted model P53114: TM-score 0.97, RMSD 1.69 Å
- 7UIC chain e against the predicted model P53114: TM-score 0.97, RMSD 1.69 Å
- 7UIL chain 3 against the predicted model P53114: TM-score 0.97, RMSD 1.69 Å
- 7UIO chain Be against the predicted model P53114: TM-score 0.97, RMSD 1.69 Å
Elsewhere
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