UniProt P52907

F-actin-capping protein subunit alpha-1 (P52907)

F-actin-capping protein subunit alpha-1 (UniProt P52907): 5 experimental structures and 1 predicted model on GenesisL1, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: P52907
Protein: F-actin-capping protein subunit alpha-1
Experimental structures: 5
Predicted models: 1
Pockets: 5 · 1 record with a druggable one

Structures

6 records of P52907 in the MolNFT archive: 5 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
1MQ1	Ca2+-S100B-TRTK-12 complex	solution nmr	C, D	—	—
1MQ1	CA2+-S100B-trtk-12 complex	solution nmr	C, D	—	—
1MWN	Solution NMR structure of S100B bound to the high-affinity target peptide TRTK-12	solution nmr	X, Y	—	—
1MWN	Solution NMR structure of S100B bound to the high-affinity target peptide trtk-12	solution nmr	X, Y	—	—
8F8Q	Cryo-EM structure of the CapZ-capped barbed end of F-actin	electron microscopy	G	—	5 (best 0.83)
P52907	AlphaFold monomer V2.0 prediction for F-actin-capping protein subunit alpha-1 (P52907)	predicted	A	—	—

Experiment against prediction

8F8Q chain G against the predicted model P52907: TM-score 0.94, RMSD 1.66 Å
1MWN chain X against the predicted model P52907: TM-score 0.52, RMSD 1.34 Å
1MWN chain X against the predicted model P52907: TM-score 0.52, RMSD 1.34 Å
1MWN chain Y against the predicted model P52907: TM-score 0.52, RMSD 1.34 Å
1MWN chain Y against the predicted model P52907: TM-score 0.52, RMSD 1.34 Å
1MQ1 chain C against the predicted model P52907: TM-score 0.28, RMSD 1.96 Å
1MQ1 chain C against the predicted model P52907: TM-score 0.28, RMSD 1.96 Å
1MQ1 chain D against the predicted model P52907: TM-score 0.28, RMSD 1.96 Å
1MQ1 chain D against the predicted model P52907: TM-score 0.28, RMSD 1.96 Å

Elsewhere

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