UniProt P52477
Multidrug resistance protein MexA (P52477)
Multidrug resistance protein MexA (UniProt P52477): 11 experimental structures and 1 predicted model on GenesisL1, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P52477
- Protein
- Multidrug resistance protein MexA
- Experimental structures
- 11
- Predicted models
- 1
- Pockets
- 8 · 1 record with a druggable one
Structures
12 records of P52477 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1T5E | The structure of MexA | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M | — | — |
| 1T5E | The structure of mexa | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M | — | — |
| 1VF7 | Crystal structure of the membrane fusion protein, MexA of the multidrug transporter | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M | — | — |
| 1VF7 | Crystal structure of the membrane fusion protein, mexa of the multidrug transporter | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M | — | — |
| 2V4D | Re-refinement of MexA adaptor protein | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M | — | — |
| 2V4D | Re-refinement of mexa adaptor protein | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M | — | — |
| 4DK1 | Crystal Structure of MacA-MexA chimeric protein, containing the Pseudomonas aeruginosa MexA… | x-ray diffraction | A, B, C, D | — | — |
| 4DK1 | Crystal structure of maca-mexa chimeric protein, containing the pseudomonas aeruginosa mexa… | x-ray diffraction | A, B, C, D | — | — |
| 6IOK | Cryo-EM structure of multidrug efflux pump MexAB-OprM (0 degree state) | electron microscopy | I, J, K, L, M, N | — | 8 (best 0.90) |
| 6IOK | Cryo-EM structure of multidrug efflux pump mexab-oprm (0 degree state) | electron microscopy | I, J, K, L, M, N | — | — |
| 6IOL | Cryo-EM structure of multidrug efflux pump mexab-oprm (60 degree state) | electron microscopy | I, J, K, L, M, N | — | — |
| P52477 | AlphaFold monomer V2.0 prediction for multidrug resistance protein mexa (P52477) | predicted | A | — | — |
Experiment against prediction
- 1VF7 chain M against the predicted model P52477: TM-score 0.94, RMSD 1.45 Å
- 1VF7 chain M against the predicted model P52477: TM-score 0.94, RMSD 1.45 Å
- 1T5E chain A against the predicted model P52477: TM-score 0.94, RMSD 1.45 Å
- 1T5E chain A against the predicted model P52477: TM-score 0.94, RMSD 1.45 Å
- 2V4D chain A against the predicted model P52477: TM-score 0.93, RMSD 1.53 Å
- 2V4D chain A against the predicted model P52477: TM-score 0.93, RMSD 1.53 Å
- 1VF7 chain H against the predicted model P52477: TM-score 0.92, RMSD 1.76 Å
- 1VF7 chain H against the predicted model P52477: TM-score 0.92, RMSD 1.76 Å
- 1VF7 chain K against the predicted model P52477: TM-score 0.91, RMSD 1.92 Å
- 1VF7 chain K against the predicted model P52477: TM-score 0.91, RMSD 1.92 Å
Elsewhere
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