UniProt P52002
Multidrug resistance protein MexB (P52002)
Multidrug resistance protein MexB (UniProt P52002): 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P52002
- Protein
- Multidrug resistance protein MexB
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 20 · 1 record with a druggable one
Structures
9 records of P52002 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2V50 | The Missing Part of the Bacterial MexAB-OprM System: Structural determination of the Multidrug… | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2V50 | The missing part of the bacterial mexab-oprm system: structural determination of the multidrug… | x-ray diffraction | A, B, C, D, E, F | — | — |
| 3W9I | Structural basis for the inhibition of bacterial multidrug exporters | x-ray diffraction | A, B, C, D, E, F | — | — |
| 3W9J | Structural basis for the inhibition of bacterial multidrug exporters | x-ray diffraction | A, B, C, D, E, F | — | — |
| 6IIA | Mexb in complex with lmng | x-ray diffraction | A, B, C, D, E, F | AV0 | — |
| 6IOK | Cryo-EM structure of multidrug efflux pump MexAB-OprM (0 degree state) | electron microscopy | F, G, E | — | 20 (best 0.90) |
| 6IOK | Cryo-EM structure of multidrug efflux pump mexab-oprm (0 degree state) | electron microscopy | F, G, E | — | — |
| 6IOL | Cryo-EM structure of multidrug efflux pump mexab-oprm (60 degree state) | electron microscopy | F, G, E | — | — |
| P52002 | AlphaFold monomer V2.0 prediction for multidrug resistance protein mexb (P52002) | predicted | A | — | — |
Ligands
- AV0 · 2-decyl-2-{[(4-O-alpha-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]methyl}dodecyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside · in 1 record
Experiment against prediction
- 3W9J chain B against the predicted model P52002: TM-score 0.98, RMSD 1.59 Å
- 6IIA chain B against the predicted model P52002: TM-score 0.98, RMSD 1.60 Å
- 6IOL chain G against the predicted model P52002: TM-score 0.98, RMSD 1.64 Å
- 6IOK chain G against the predicted model P52002: TM-score 0.98, RMSD 1.66 Å
- 6IOK chain G against the predicted model P52002: TM-score 0.98, RMSD 1.66 Å
- 6IOL chain F against the predicted model P52002: TM-score 0.98, RMSD 1.64 Å
- 3W9I chain B against the predicted model P52002: TM-score 0.98, RMSD 1.66 Å
- 2V50 chain E against the predicted model P52002: TM-score 0.98, RMSD 1.71 Å
- 2V50 chain E against the predicted model P52002: TM-score 0.98, RMSD 1.71 Å
- 2V50 chain B against the predicted model P52002: TM-score 0.98, RMSD 1.73 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.