UniProt P51970

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (P51970)

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (UniProt P51970): 5 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 11 pockets. Binding sites, druggability and experiment against…

UniProt: P51970
Protein: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8
Experimental structures: 5
Predicted models: 1
Ligands: 1
Pockets: 11 · 3 records with a druggable one

Structures

6 records of P51970 in the MolNFT archive: 5 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
5XTC	Cryo-EM structure of human respiratory complex I transmembrane arm	electron microscopy	u	CDL	6 (best 0.86)
5XTC	Cryo-EM structure of human respiratory complex I transmembrane arm	electron microscopy	u	CDL	—
5XTD	Cryo-EM structure of human respiratory complex I	electron microscopy	u	CDL	—
5XTH	Cryo-EM structure of human respiratory supercomplex I1III2IV1	electron microscopy	u	CDL	2 (best 0.86)
5XTI	Cryo-EM architecture of human respiratory chain megacomplex-I2III2IV2	electron microscopy	u, Bu	CDL	2 (best 0.87)
P51970	AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8…	predicted	A	—	1 (best 0.28)

Ligands

CDL · Cardiolipin · in 5 records

Experiment against prediction

5XTC chain u against the predicted model P51970: TM-score 0.92, RMSD 1.56 Å
5XTC chain u against the predicted model P51970: TM-score 0.92, RMSD 1.56 Å
5XTH chain u against the predicted model P51970: TM-score 0.92, RMSD 1.56 Å
5XTI chain Bu against the predicted model P51970: TM-score 0.92, RMSD 1.56 Å
5XTI chain u against the predicted model P51970: TM-score 0.92, RMSD 1.56 Å
5XTD chain u against the predicted model P51970: TM-score 0.92, RMSD 1.56 Å

Elsewhere

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