UniProt P51797
H(+)/Cl(-) exchange transporter 6 (P51797)
H(+)/Cl(-) exchange transporter 6 (UniProt P51797): 3 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 54 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P51797
- Protein
- H(+)/Cl(-) exchange transporter 6
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 54 · 3 records with a druggable one
Structures
4 records of P51797 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8JPJ | Cryo-EM structure of ClC-6 apo state | electron microscopy | A, B | CL | 18 (best 0.87) |
| 8JPO | Cryo-EM structure of ATP bound human ClC-6 | electron microscopy | A, B | CL, MG, ATP | 20 (best 0.84) |
| 8JPR | Cryo-EM structure of Y553C human ClC-6 | electron microscopy | A, B | CL, MG, ATP | 16 (best 0.85) |
| P51797 | AlphaFold monomer V2.0 prediction for chloride transport protein 6 (P51797) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8JPR chain B against the predicted model P51797: TM-score 0.95, RMSD 1.55 Å
- 8JPR chain A against the predicted model P51797: TM-score 0.95, RMSD 1.55 Å
- 8JPO chain B against the predicted model P51797: TM-score 0.95, RMSD 1.60 Å
- 8JPO chain A against the predicted model P51797: TM-score 0.95, RMSD 1.61 Å
- 8JPJ chain A against the predicted model P51797: TM-score 0.95, RMSD 1.74 Å
- 8JPJ chain B against the predicted model P51797: TM-score 0.95, RMSD 1.74 Å
Elsewhere
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