UniProt P51685
C-C chemokine receptor type 8,Fusion protein (P51685)
C-C chemokine receptor type 8,Fusion protein (UniProt P51685): 3 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P51685
- Protein
- C-C chemokine receptor type 8,Fusion protein
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 8 · 3 records with a druggable one
Structures
4 records of P51685 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8KFX | Gi bound CCR8 complex with nonpeptide agonist LMD-009 | electron microscopy | R | OS9 | 2 (best 0.74) |
| 8KFY | Gi bound CCR8 complex with nonpeptide agonist ZK 756326 | electron microscopy | R | OXF | 2 (best 0.72) |
| 8U1U | Structure of a class A GPCR/agonist complex | electron microscopy | A | NAG | 4 (best 0.78) |
| P51685 | AlphaFold monomer V2.0 prediction for C-C chemokine receptor type 8 (P51685) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8KFX chain R against the predicted model P51685: TM-score 0.94, RMSD 1.76 Å
- 8KFY chain R against the predicted model P51685: TM-score 0.94, RMSD 1.81 Å
- 8U1U chain A against the predicted model P51685: TM-score 0.75, RMSD 2.61 Å
- 8U1U chain A against the predicted model P22362: TM-score 0.18, RMSD 2.36 Å
Elsewhere
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