UniProt P51170
Amiloride-sensitive sodium channel subunit gamma (P51170)
Amiloride-sensitive sodium channel subunit gamma (UniProt P51170): 4 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 37 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- P51170
- Protein
- Amiloride-sensitive sodium channel subunit gamma
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 37 · 4 records with a druggable one
Structures
5 records of P51170 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6WTH | Full-length human ENaC ECD | electron microscopy | C | NAG | 8 (best 0.90) |
| 6WTH | Full-length human ENAC ecd | electron microscopy | C | NAG | — |
| 9BLR | Human SCNN1D-SCNN1B-SCNN1G ENaC trimer | electron microscopy | C | NAG | 12 (best 0.86) |
| 9BTU | Human SCNN1B-SCNN1G ENaC dimers | electron microscopy | C | NAG | 10 (best 0.89) |
| P51170 | AlphaFold monomer V2.0 prediction for amiloride-sensitive sodium channel subunit gamma (P51170) | predicted | A | — | 7 (best 0.62) |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 4 records
Experiment against prediction
- 6WTH chain C against the predicted model P51170: TM-score 0.97, RMSD 1.43 Å
- 6WTH chain C against the predicted model P51170: TM-score 0.97, RMSD 1.43 Å
- 9BLR chain C against the predicted model P51170: TM-score 0.95, RMSD 1.66 Å
- 9BTU chain C against the predicted model P51170: TM-score 0.94, RMSD 1.78 Å
Elsewhere
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