UniProt P50465
Endonuclease 8 (P50465)
Endonuclease 8 (UniProt P50465), EC 3.2.2.-, 4.2.99.18: 18 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P50465
- Protein
- Endonuclease 8
- EC
- 3.2.2.-, 4.2.99.18
- Experimental structures
- 18
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 3 · 1 record with a druggable one
Structures
19 records of P50465 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1K3W | Crystal structure of a trapped reaction intermediate of the DNA Repair Enzyme Endonuclease VIII… | x-ray diffraction | A | — | — |
| 1K3W | Crystal structure of a trapped reaction intermediate of the DNA repair enzyme endonuclease VIII… | x-ray diffraction | A | — | — |
| 1K3X | Crystal structure of a trapped reaction intermediate of the DNA repair enzyme Endonuclease VIII… | x-ray diffraction | A | — | — |
| 1K3X | Crystal structure of a trapped reaction intermediate of the DNA repair enzyme endonuclease VIII… | x-ray diffraction | A | — | — |
| 1Q39 | Crystal structure of the DNA repair enzyme endonuclease-VIII (Nei) from E. coli: The WT enzyme at… | x-ray diffraction | A | — | — |
| 1Q39 | Crystal structure of the DNA repair enzyme endonuclease-VIII (nei) from E. COLI: the wt enzyme at… | x-ray diffraction | A | — | — |
| 1Q3B | Crystal structure of the DNA repair enzyme endonuclease-VIII (Nei) from E. coli: The R252A mutant… | x-ray diffraction | A | — | — |
| 1Q3B | Crystal structure of the DNA repair enzyme endonuclease-VIII (nei) from E. COLI: the R252A mutant… | x-ray diffraction | A | — | — |
| 1Q3C | Crystal structure of the DNA repair enzyme endonuclease-VIII (Nei) from E. coli: The E2A mutant at… | x-ray diffraction | A | — | — |
| 1Q3C | Crystal structure of the DNA repair enzyme endonuclease-VIII (nei) from E. COLI: the E2A mutant at… | x-ray diffraction | A | — | — |
| 2EA0 | Crystal structure of the DNA repair enzyme endonuclease-VIII (Nei) from E. coli in complex with… | x-ray diffraction | A | — | — |
| 2EA0 | Crystal structure of the DNA repair enzyme endonuclease-VIII (nei) from E. COLI in complex with… | x-ray diffraction | A | — | — |
| 2OPF | Crystal structure of the DNA repair enzyme endonuclease-VIII (Nei) from E. coli (R252A) in complex… | x-ray diffraction | A | — | — |
| 2OPF | Crystal structure of the DNA repair enzyme endonuclease-VIII (nei) from E. COLI (R252A) in complex… | x-ray diffraction | A | — | — |
| 2OQ4 | Crystal structure of the DNA repair enzyme endonuclease-VIII (Nei) from E. coli (E2Q) in complex… | x-ray diffraction | A, B | — | — |
| 2OQ4 | Crystal structure of the DNA repair enzyme endonuclease-VIII (nei) from E. COLI (E2Q) in complex… | x-ray diffraction | A, B | — | — |
| 6FBU | Crystal structure of the DNA repair enzyme endonuclease-VIII (Nei) from E. coli (E2Q) in complex… | x-ray diffraction | A | SO4, ZN | 3 (best 0.62) |
| 6FBU | Crystal structure of the DNA repair enzyme endonuclease-VIII (nei) from E. COLI (E2Q) in complex… | x-ray diffraction | A | SO4, ZN | — |
| P50465 | AlphaFold monomer V2.0 prediction for endonuclease 8 (P50465) | predicted | A | — | — |
Ligands
Experiment against prediction
- 2OQ4 chain A against the predicted model P50465: TM-score 0.99, RMSD 0.56 Å
- 2OQ4 chain A against the predicted model P50465: TM-score 0.99, RMSD 0.56 Å
- 6FBU chain A against the predicted model P50465: TM-score 0.99, RMSD 0.62 Å
- 6FBU chain A against the predicted model P50465: TM-score 0.99, RMSD 0.62 Å
- 2OQ4 chain B against the predicted model P50465: TM-score 0.99, RMSD 0.66 Å
- 2OQ4 chain B against the predicted model P50465: TM-score 0.99, RMSD 0.66 Å
- 1K3W chain A against the predicted model P50465: TM-score 0.99, RMSD 0.68 Å
- 1K3W chain A against the predicted model P50465: TM-score 0.99, RMSD 0.68 Å
- 2EA0 chain A against the predicted model P50465: TM-score 0.99, RMSD 0.70 Å
- 2EA0 chain A against the predicted model P50465: TM-score 0.99, RMSD 0.70 Å
Elsewhere
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