UniProt P50102
Ubiquitin carboxyl-terminal hydrolase 8 (P50102)
Ubiquitin carboxyl-terminal hydrolase 8 (UniProt P50102), EC 3.4.19.12: 19 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 18 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P50102
- Protein
- Ubiquitin carboxyl-terminal hydrolase 8
- EC
- 3.4.19.12
- Experimental structures
- 19
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 18 · 2 records with a druggable one
Structures
20 records of P50102 in the MolNFT archive: 19 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3M99 | Structure of the Ubp8-Sgf11-Sgf73-Sus1 SAGA DUB module | x-ray diffraction | A | — | — |
| 3M99 | Structure of the UBP8-SGF11-SGF73-SUS1 saga dub module | x-ray diffraction | A | — | — |
| 3MHH | Structure of the SAGA Ubp8/Sgf11/Sus1/Sgf73 DUB module | x-ray diffraction | A | — | — |
| 3MHH | Structure of the saga UBP8/SGF11/SUS1/SGF73 dub module | x-ray diffraction | A | — | — |
| 3MHS | Structure of the SAGA Ubp8/Sgf11/Sus1/Sgf73 DUB module bound to ubiquitin aldehyde | x-ray diffraction | A | — | — |
| 3MHS | Structure of the saga UBP8/SGF11/SUS1/SGF73 dub module bound to ubiquitin aldehyde | x-ray diffraction | A | — | — |
| 4FIP | Structure of the SAGA Ubp8(S144N)/Sgf11(1-72, Delta-ZnF)/Sus1/Sgf73 DUB module | x-ray diffraction | A, E | — | — |
| 4FIP | Structure of the saga UBP8(S144N)/SGF11(1-72, delta-ZNF)/SUS1/SGF73 dub module | x-ray diffraction | A, E | — | — |
| 4FJC | Structure of the SAGA Ubp8/Sgf11(1-72, Delta-ZnF)/Sus1/Sgf73 DUB module | x-ray diffraction | A, E | — | — |
| 4FJC | Structure of the saga UBP8/SGF11(1-72, delta-ZNF)/SUS1/SGF73 dub module | x-ray diffraction | A, E | — | — |
| 4FK5 | Structure of the SAGA Ubp8(S144N)/Sgf11/Sus1/Sgf73 DUB module | x-ray diffraction | A | — | — |
| 4FK5 | Structure of the saga UBP8(S144N)/SGF11/SUS1/SGF73 dub module | x-ray diffraction | A | — | — |
| 4WA6 | Structure of yeast SAGA DUBm with Sgf73 N59D mutant at 2.36 angstroms resolution | x-ray diffraction | A, D | — | — |
| 4WA6 | Structure of yeast saga dubm with SGF73 N59D mutant at 2.36 ångströms resolution | x-ray diffraction | A, D | — | — |
| 4ZUX | Saga dub module UBP8/SGF11/SUS1/SGF73 bound to ubiqitinated nucleosome | x-ray diffraction | U, Z, e, j | — | — |
| 6AQR | SAGA DUB module Ubp8(C146A)/Sgf11/Sus1/Sgf73 bound to monoubiquitin | x-ray diffraction | A | ZN | 9 (best 0.85) |
| 6AQR | Saga dub module UBP8(C146A)/SGF11/SUS1/SGF73 bound to monoubiquitin | x-ray diffraction | A | ZN | — |
| 6T9L | SAGA DUB module bound to a ubiqitinated nucleosome | electron microscopy | K | ZN | 5 (best 0.83) |
| 6T9L | Saga dub module bound to a ubiqitinated nucleosome | electron microscopy | K | ZN | — |
| P50102 | AlphaFold monomer V2.0 prediction for ubiquitin carboxyl-terminal hydrolase 8 (P50102) | predicted | A | — | 4 (best 0.42) |
Ligands
- ZN · Zinc ion · in 4 records
Experiment against prediction
- 4ZUX chain U against the predicted model P50102: TM-score 0.99, RMSD 0.70 Å
- 3MHS chain A against the predicted model P50102: TM-score 0.99, RMSD 0.73 Å
- 3MHS chain A against the predicted model P50102: TM-score 0.99, RMSD 0.73 Å
- 4ZUX chain e against the predicted model P50102: TM-score 0.99, RMSD 0.73 Å
- 4ZUX chain Z against the predicted model P50102: TM-score 0.99, RMSD 0.74 Å
- 4ZUX chain j against the predicted model P50102: TM-score 0.99, RMSD 0.77 Å
- 6AQR chain A against the predicted model P50102: TM-score 0.99, RMSD 0.86 Å
- 6AQR chain A against the predicted model P50102: TM-score 0.99, RMSD 0.86 Å
- 3M99 chain A against the predicted model P50102: TM-score 0.98, RMSD 1.25 Å
- 3M99 chain A against the predicted model P50102: TM-score 0.98, RMSD 1.25 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.