UniProt P49862
Kallikrein-7 (P49862)
Kallikrein-7 (UniProt P49862), EC 3.4.21.117: 21 experimental structures on GenesisL1, 8 ligands bound, 24 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P49862
- Protein
- Kallikrein-7
- EC
- 3.4.21.117
- Experimental structures
- 21
- Predicted models
- 0
- Ligands
- 8
- Pockets
- 24 · 3 records with a druggable one
Structures
21 records of P49862 in the MolNFT archive: 21 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2QXG | Crystal Structure of Human Kallikrein 7 in Complex with Ala-Ala-Phe-chloromethylketone | x-ray diffraction | A, B | — | — |
| 2QXG | Crystal structure of human kallikrein 7 in complex with ala- ala-phe-chloromethylketone | x-ray diffraction | A, B | — | — |
| 2QXH | Crystal Structure of Human Kallikrein 7 in Complex with Suc-Ala-Ala-Pro-Phe-chloromethylketone | x-ray diffraction | A | — | — |
| 2QXH | Crystal structure of human kallikrein 7 in complex with suc- ala-ala-pro-phe-chloromethylketone | x-ray diffraction | A | — | — |
| 2QXI | High resolution structure of Human Kallikrein 7 in Complex with… | x-ray diffraction | A | — | — |
| 2QXI | High resolution structure of human kallikrein 7 in complex with suc… | x-ray diffraction | A | — | — |
| 2QXJ | Crystal Structure of Human Kallikrein 7 in Complex with Suc-Ala-Ala-Pro-Phe-chloromethylketone and… | x-ray diffraction | A | — | — |
| 2QXJ | Crystal structure of human kallikrein 7 in complex with suc- ala-ala-pro-phe-chloromethylketone and… | x-ray diffraction | A | — | — |
| 3BSQ | Crystal structure of human kallikrein 7 produced as a secretion protein in E.coli | x-ray diffraction | A, B, C | — | — |
| 3BSQ | Crystal structure of human kallikrein 7 produced as a secretion protein in E.COLI | x-ray diffraction | A, B, C | — | — |
| 5FAH | Kallikrein-7 in complex with COMPOUND1 | x-ray diffraction | A | 5VT | 1 (best 0.52) |
| 5FAH | Kallikrein-7 in complex with COMPOUND1 | x-ray diffraction | A | — | — |
| 5Y9L | Human kallikrein 7 in complex with 1,3,6-trisubstituted 1,4-diazepane- 7-one | x-ray diffraction | A | 8R3, CL | — |
| 5YJK | Human kallikrein 7 in complex with 1,4-diazepane-7-one 1-acetamide derivative | x-ray diffraction | A | 8VX, CL | — |
| 6SHH | Human kallikrein 7 with aromatic coumarinic ester compound 1 covalently bound to H57 | x-ray diffraction | A, B, C, D, E, F, G, H | SO4, SH7 | 16 (best 0.88) |
| 6SHH | Human kallikrein 7 with aromatic coumarinic ester compound 1 covalently bound to H57 | x-ray diffraction | A, B, C, D, E, F, G, H | SO4, SH7 | — |
| 6SHI | Human kallikrein 7 with aromatic coumarinic ester compound 2 covalently bound to H57 | x-ray diffraction | A, B, C, D, E, F, G, H | SH8, SO4 | — |
| 6SJU | Human kallikrein 7 with aromatic coumarinic ester compound 3 covalently bound to H57 | x-ray diffraction | A, B, C, D, E, F, G, H | SO4, LFW | — |
| 6Y4S | Human kallikrein-related peptidase 7 (KLK7) in the unliganded state | x-ray diffraction | A, B, C | SO4 | 7 (best 0.83) |
| 6Y4S | Human kallikrein-related peptidase 7 (KLK7) in the unliganded state | x-ray diffraction | A, B, C | SO4 | — |
| P49862 | AlphaFold monomer V2.0 prediction for kallikrein-7 (P49862) | — | — | — |
Ligands
- SO4 · Sulfate ion · in 6 records
- CL · Chloride ion · in 2 records
- SH7 · (3-chlorophenyl) 6-methyl-2-oxidanylidene-chromene-3-carboxylate · in 2 records
- 5VT · (2~{S})-~{N}2-[2-(4-methoxyphenyl)ethyl]-~{N}1-(naphthalen-1-ylmethyl)pyrrolidine-1,2-dicarboxamide · in 1 record
- 8R3 · 3-[2-[(3Z,6R)-6-[(5-chloranyl-2-methoxy-phenyl)methyl]-3-(dimethylhydrazinylidene)-7-oxidanylidene-1,4-diazepan-1-yl]ethanoylamino]benzoic acid · in 1 record
- 8VX · (R)-2-(6-(5-chloro-2-methoxybenzyl)-3-(2,2-dimethylhydrazono)-7-oxo-1,4-diazepan-1-yl)-N-(3-(methylsulfonyl)phenyl)acetamide · in 1 record
- LFW · (3-iodanylphenyl) 6-methyl-2-oxidanylidene-chromene-3-carboxylate · in 1 record
- SH8 · 6-methyl-2-oxidanylidene-chromene-3-carboxylic acid · in 1 record
Elsewhere
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