UniProt P49735
DNA replication licensing factor Mcm2 (P49735)
DNA replication licensing factor Mcm2 (UniProt P49735), EC 3.6.4.12: 6 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 7 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P49735
- Protein
- DNA replication licensing factor Mcm2
- EC
- 3.6.4.12
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 7 · 1 record with a druggable one
Structures
7 records of P49735 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6RAW | D. melanogaster cmg-DNA, state 1A | electron microscopy | 2 | ATP | — |
| 6RAX | D. melanogaster CMG-DNA, State 1B | electron microscopy | 2 | ATP | — |
| 6RAX | D. melanogaster cmg-DNA, state 1B | electron microscopy | 2 | ATP | — |
| 6RAY | D. melanogaster cmg-DNA, state 2A | electron microscopy | 2 | ATP | — |
| 6RAZ | D. melanogaster CMG-DNA, State 2B | electron microscopy | 2 | ADP | 7 (best 0.89) |
| 6RAZ | D. melanogaster cmg-DNA, state 2B | electron microscopy | 2 | ADP | — |
| P49735 | AlphaFold monomer V2.0 prediction for DNA replication licensing factor MCM2 (P49735) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6RAX chain 2 against the predicted model P49735: TM-score 0.90, RMSD 3.16 Å
- 6RAX chain 2 against the predicted model P49735: TM-score 0.90, RMSD 3.16 Å
- 6RAW chain 2 against the predicted model P49735: TM-score 0.89, RMSD 3.27 Å
- 6RAY chain 2 against the predicted model P49735: TM-score 0.85, RMSD 3.76 Å
- 6RAZ chain 2 against the predicted model P49735: TM-score 0.81, RMSD 4.31 Å
- 6RAZ chain 2 against the predicted model P49735: TM-score 0.81, RMSD 4.31 Å
Elsewhere
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