UniProt P49715
Tribbles homolog 1,CCAAT/enhancer-binding protein alpha (P49715)
Tribbles homolog 1,CCAAT/enhancer-binding protein alpha (UniProt P49715): 2 experimental structures and 1 predicted model on GenesisL1, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P49715
- Protein
- Tribbles homolog 1,CCAAT/enhancer-binding protein alpha
- Experimental structures
- 2
- Predicted models
- 1
- Pockets
- 6 · 1 record with a druggable one
Structures
3 records of P49715 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6DC0 | Tribbles (TRIB1) pseudokinase fused to CCAAT-enhancer binding protein (C/EBPalpha) degron | x-ray diffraction | A, B | — | 6 (best 0.60) |
| 6DC0 | Tribbles (TRIB1) pseudokinase fused to ccaat-enhancer binding protein (C/EBPALPHA) degron | x-ray diffraction | A, B | — | — |
| P49715 | AlphaFold monomer V2.0 prediction for CCAAT/ENHANCER-binding protein alpha (P49715) | predicted | A | — | — |
Experiment against prediction
- 6DC0 chain B against the predicted model P49715: TM-score 0.15, RMSD 5.75 Å
- 6DC0 chain B against the predicted model P49715: TM-score 0.15, RMSD 5.75 Å
- 6DC0 chain A against the predicted model P49715: TM-score 0.15, RMSD 6.90 Å
- 6DC0 chain A against the predicted model P49715: TM-score 0.15, RMSD 6.90 Å
Elsewhere
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