UniProt P49674

Casein kinase I isoform epsilon (P49674)

Casein kinase I isoform epsilon (UniProt P49674): 4 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: P49674
Protein: Casein kinase I isoform epsilon
Experimental structures: 4
Predicted models: 1
Pockets: 3 · 1 record with a druggable one

Structures

5 records of P49674 in the MolNFT archive: 4 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
4HNI	crystal structure of ck1e in complex with PF4800567	x-ray diffraction	A, B	—	—
4HNI	Crystal structure of CK1E in complex with PF4800567	x-ray diffraction	A, B	—	—
4HOK	crystal structure of apo ck1e	x-ray diffraction	A, C, E, G, I, K, M, O, Q, S, U, W	—	—
4HOK	Crystal structure of apo CK1E	x-ray diffraction	A, C, E, G, I, K, M, O, Q, S, U, W	—	—
P49674	AlphaFold monomer V2.0 prediction for casein kinase I isoform epsilon (P49674)	predicted	A	—	3 (best 0.77)

Experiment against prediction

4HNI chain B against the predicted model P49674: TM-score 0.98, RMSD 0.90 Å
4HNI chain B against the predicted model P49674: TM-score 0.98, RMSD 0.90 Å
4HNI chain A against the predicted model P49674: TM-score 0.98, RMSD 0.95 Å
4HNI chain A against the predicted model P49674: TM-score 0.98, RMSD 0.95 Å
4HOK chain S against the predicted model P49674: TM-score 0.97, RMSD 1.14 Å
4HOK chain S against the predicted model P49674: TM-score 0.97, RMSD 1.14 Å
4HOK chain U against the predicted model P49674: TM-score 0.97, RMSD 1.18 Å
4HOK chain U against the predicted model P49674: TM-score 0.97, RMSD 1.18 Å
4HOK chain E against the predicted model P49674: TM-score 0.96, RMSD 1.32 Å
4HOK chain E against the predicted model P49674: TM-score 0.96, RMSD 1.32 Å

Elsewhere

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.