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UniProt P49638

Alpha-tocopherol transfer protein (P49638)

Alpha-tocopherol transfer protein (UniProt P49638): 12 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt
P49638
Protein
Alpha-tocopherol transfer protein
Experimental structures
12
Predicted models
1
Ligands
4
Pockets
7 · 3 records with a druggable one

Structures

13 records of P49638 in the MolNFT archive: 12 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
1OIPThe Molecular Basis of Vitamin E Retention: Structure of Human Alpha-Tocopherol Transfer Proteinx-ray diffractionA——
1OIPThe molecular basis of vitamin E retention: structure of human alpha-tocopherol transfer proteinx-ray diffractionA——
1OIZThe Molecular Basis of Vitamin E Retention: Structure of Human Alpha-Tocopherol Transfer Proteinx-ray diffractionA, B——
1OIZThe molecular basis of vitamin E retention: structure of human alpha-tocopherol transfer proteinx-ray diffractionA, B——
1R5LCrystal Structure of Human Alpha-Tocopherol Transfer Protein Bound to its Ligandx-ray diffractionA——
1R5LCrystal structure of human alpha-tocopherol transfer protein bound to its ligandx-ray diffractionA——
5MUESelf-assembled alpha-Tocopherol Transfer Protein Nanoparticles Promote Vitamin E Delivery Across an…x-ray diffractionASO4, VIV, CL, ETA3 (best 0.87)
5MUESelf-assembled alpha-tocopherol transfer protein nanoparticles promote vitamin E delivery across an…x-ray diffractionASO4, VIV, CL, ETA—
5MUGSelf-assembled alpha-Tocopherol Transfer Protein Nanoparticles Promote Vitamin E Delivery Across an…x-ray diffractionAVIV, SO4, CL—
5MUGSelf-assembled alpha-tocopherol transfer protein nanoparticles promote vitamin E delivery across an…x-ray diffractionAVIV, SO4, CL, ETA—
6ZPDgamma-tocopherol transfer proteinx-ray diffractionAVIV, SO4, CL2 (best 0.87)
6ZPDGamma-tocopherol transfer proteinx-ray diffractionAVIV, SO4, CL—
P49638AlphaFold monomer V2.0 prediction for alpha-tocopherol transfer protein (P49638)predictedA—2 (best 0.87)

Ligands

  • CL · Chloride ion · in 6 records
  • SO4 · Sulfate ion · in 6 records
  • VIV · (2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]chroman-6-ol · in 6 records
  • ETA · Ethanolamine · in 3 records

Experiment against prediction

Elsewhere

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