UniProt P49588
Alanine--tRNA ligase, cytoplasmic (P49588)
Alanine--tRNA ligase, cytoplasmic (UniProt P49588), EC 6.1.1.7: 11 experimental structures on GenesisL1, 2 ligands bound, 22 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P49588
- Protein
- Alanine--tRNA ligase, cytoplasmic
- EC
- 6.1.1.7
- Experimental structures
- 11
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 22 · 2 records with a druggable one
Structures
11 records of P49588 in the MolNFT archive: 11 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4XEM | Crystal Structure of wild type human AlaRS catalytic domain | x-ray diffraction | A | — | — |
| 4XEM | Crystal structure of wild type human alars catalytic domain | x-ray diffraction | A | — | — |
| 4XEO | Crystal Structure of human AlaRS catalytic domain with R329H mutation | x-ray diffraction | A, B | — | — |
| 4XEO | Crystal structure of human alars catalytic domain with R329H mutation | x-ray diffraction | A, B | — | — |
| 5KNN | Evolutionary gain of alanine mischarging to non-cognate tRNAs with a G4:U69 base pair | x-ray diffraction | A, B, C, D, E, F, G, H | A5A | 20 (best 0.78) |
| 5KNN | Evolutionary gain of alanine mischarging to non-cognate trnas with a G4:U69 base pair | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 5T5S | A fragment of a human tRNA synthetase | x-ray diffraction | A | — | — |
| 5T76 | A fragment of a human tRNA synthetase | x-ray diffraction | A | — | — |
| 5V59 | Crystal structure of catalytic fragment of human AlaRS in complex with Aze-SA | x-ray diffraction | A | 8X1 | 2 (best 0.67) |
| 5V59 | Crystal structure of catalytic fragment of human alars in complex with aze-sa | x-ray diffraction | A | — | — |
| P49588 | AlphaFold monomer V2.0 prediction for alanine--tRNA ligase, cytoplasmic (P49588) | — | — | — |
Ligands
Elsewhere
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