UniProt P49448
Glutamate dehydrogenase 2, mitochondrial (P49448)
Glutamate dehydrogenase 2, mitochondrial (UniProt P49448), EC 1.4.1.3: 2 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 20 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P49448
- Protein
- Glutamate dehydrogenase 2, mitochondrial
- EC
- 1.4.1.3
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 20 · 1 record with a druggable one
Structures
3 records of P49448 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6G2U | Crystal structure of the human glutamate dehydrogenase 2 (hGDH2) | x-ray diffraction | A, B, C, D, E, F | PO4, NA, CL | 20 (best 0.88) |
| 6G2U | Crystal structure of the human glutamate dehydrogenase 2 (HGDH2) | x-ray diffraction | A, B, C, D, E, F | PO4, NA, CL | — |
| P49448 | AlphaFold monomer V2.0 prediction for glutamate dehydrogenase 2, mitochondrial (P49448) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6G2U chain E against the predicted model P49448: TM-score 0.95, RMSD 1.97 Å
- 6G2U chain E against the predicted model P49448: TM-score 0.95, RMSD 1.97 Å
- 6G2U chain A against the predicted model P49448: TM-score 0.95, RMSD 2.01 Å
- 6G2U chain A against the predicted model P49448: TM-score 0.95, RMSD 2.01 Å
- 6G2U chain D against the predicted model P49448: TM-score 0.95, RMSD 2.06 Å
- 6G2U chain D against the predicted model P49448: TM-score 0.95, RMSD 2.06 Å
- 6G2U chain C against the predicted model P49448: TM-score 0.95, RMSD 2.03 Å
- 6G2U chain C against the predicted model P49448: TM-score 0.95, RMSD 2.03 Å
- 6G2U chain F against the predicted model P49448: TM-score 0.94, RMSD 2.10 Å
- 6G2U chain F against the predicted model P49448: TM-score 0.94, RMSD 2.10 Å
Elsewhere
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