UniProt P49334
Mitochondrial import receptor subunit TOM22 (P49334)
Mitochondrial import receptor subunit TOM22 (UniProt P49334): 5 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 14 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P49334
- Protein
- Mitochondrial import receptor subunit TOM22
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 14 · 2 records with a druggable one
Structures
6 records of P49334 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6JNF | Cryo-EM structure of the translocator of the outer mitochondrial membrane | electron microscopy | C, H | 46E | — |
| 6UCU | Cryo-EM structure of the mitochondrial TOM complex from yeast (dimer) | electron microscopy | B, J | — | 7 (best 0.84) |
| 6UCU | Cryo-EM structure of the mitochondrial tom complex from yeast (dimer) | electron microscopy | B, J | — | — |
| 6UCV | Cryo-EM structure of the mitochondrial tom complex from yeast (tetramer) | electron microscopy | B, J, b, j | MC3 | — |
| 8XKW | Structure of the TOM40 complex unannealed | electron microscopy | B, G | — | 7 (best 0.85) |
| P49334 | AlphaFold monomer V2.0 prediction for mitochondrial import receptor subunit TOM22 (P49334) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6UCV chain B against the predicted model P49334: TM-score 0.85, RMSD 1.07 Å
- 6UCV chain J against the predicted model P49334: TM-score 0.84, RMSD 1.17 Å
- 6UCV chain b against the predicted model P49334: TM-score 0.84, RMSD 1.13 Å
- 6UCU chain B against the predicted model P49334: TM-score 0.83, RMSD 1.17 Å
- 6UCU chain B against the predicted model P49334: TM-score 0.83, RMSD 1.17 Å
- 8XKW chain B against the predicted model P49334: TM-score 0.82, RMSD 1.12 Å
- 6JNF chain C against the predicted model P49334: TM-score 0.69, RMSD 1.60 Å
Elsewhere
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