UniProt P49279
Natural resistance-associated macrophage protein 1 (P49279)
Natural resistance-associated macrophage protein 1 (UniProt P49279): 2 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 20 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P49279
- Protein
- Natural resistance-associated macrophage protein 1
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 20 · 3 records with a druggable one
Structures
3 records of P49279 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 9F6P | Human NRAMP1 (SLC11A1) in complex with manganese, towards the inward-open state | electron microscopy | A | MN | 6 (best 0.53) |
| 9F6Q | Human NRAMP1 (SLC11A1) in an occluded state | electron microscopy | A | — | 8 (best 0.70) |
| P49279 | AlphaFold monomer V2.0 prediction for natural resistance-associated macrophage protein 1 (P49279) | predicted | A | — | 6 (best 0.62) |
Ligands
- MN · Manganese (II) ion · in 1 record
Experiment against prediction
- 9F6Q chain A against the predicted model P49279: TM-score 0.97, RMSD 1.49 Å
- 9F6P chain A against the predicted model P49279: TM-score 0.96, RMSD 1.66 Å
Elsewhere
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