UniProt P49146
Neuropeptide Y receptor type 2 (P49146)
Neuropeptide Y receptor type 2 (UniProt P49146): 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 18 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P49146
- Protein
- Neuropeptide Y receptor type 2
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 18 · 3 records with a druggable one
Structures
5 records of P49146 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7DDZ | The crystal structure of human neuropeptide Y Y2 receptor with jnj- 31020028 | x-ray diffraction | A | H46, FMN | — |
| 7X9B | Cryo-EM structure of neuropeptide Y Y2 receptor in complex with NPY and Gi | electron microscopy | R | — | 7 (best 0.71) |
| 7X9B | Cryo-EM structure of neuropeptide Y Y2 receptor in complex with npy and gi | electron microscopy | R | — | — |
| 8K6N | Structural complex of neuropeptide Y receptor 2 | electron microscopy | E | — | 8 (best 0.74) |
| P49146 | AlphaFold monomer V2.0 prediction for neuropeptide Y receptor type 2 (P49146) | predicted | A | — | 3 (best 0.80) |
Ligands
Experiment against prediction
- 7DDZ chain A against the predicted model P00323: TM-score 0.34, RMSD 0.43 Å
- 7X9B chain R against the predicted model P49146: TM-score 0.91, RMSD 2.41 Å
- 7X9B chain R against the predicted model P49146: TM-score 0.91, RMSD 2.41 Å
- 8K6N chain E against the predicted model P49146: TM-score 0.89, RMSD 2.55 Å
- 7DDZ chain A against the predicted model P49146: TM-score 0.65, RMSD 2.01 Å
Elsewhere
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