UniProt P49069
Calcium signal-modulating cyclophilin ligand (P49069)
Calcium signal-modulating cyclophilin ligand (UniProt P49069): 4 experimental structures and 1 predicted model on GenesisL1, 27 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P49069
- Protein
- Calcium signal-modulating cyclophilin ligand
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 27 · 3 records with a druggable one
Structures
5 records of P49069 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6SO5 | Homo sapiens WRB/CAML heterotetramer in complex with a TRC40 dimer | electron microscopy | E, F | — | 9 (best 0.85) |
| 6SO5 | Homo sapiens WRB/CAML heterotetramer in complex with a TRC40 dimer | electron microscopy | E, F | — | — |
| 8CR1 | Homo sapiens Get1/Get2 heterotetramer in complex with a Get3 dimer | electron microscopy | C, D | — | 15 (best 0.86) |
| 8CR2 | Homo sapiens Get1/Get2 heterotetramer (a3' deletion variant) in complex with a Get3 dimer | electron microscopy | C, D | — | 3 (best 0.83) |
| P49069 | AlphaFold monomer V2.0 prediction for calcium signal-modulating cyclophilin ligand (P49069) | predicted | A | — | — |
Experiment against prediction
- 6SO5 chain E against the predicted model P49069: TM-score 0.82, RMSD 2.02 Å
- 6SO5 chain E against the predicted model P49069: TM-score 0.82, RMSD 2.02 Å
- 6SO5 chain F against the predicted model P49069: TM-score 0.77, RMSD 2.19 Å
- 6SO5 chain F against the predicted model P49069: TM-score 0.77, RMSD 2.19 Å
- 8CR2 chain C against the predicted model O00258: TM-score 0.72, RMSD 2.90 Å
- 8CR1 chain C against the predicted model O00258: TM-score 0.49, RMSD 3.67 Å
- 8CR1 chain D against the predicted model O00258: TM-score 0.49, RMSD 3.67 Å
- 8CR2 chain D against the predicted model O00258: TM-score 0.45, RMSD 4.02 Å
- 8CR2 chain C against the predicted model P49069: TM-score 0.45, RMSD 3.08 Å
- 8CR1 chain D against the predicted model P49069: TM-score 0.35, RMSD 2.05 Å
Elsewhere
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