UniProt P49054
Plasminogen-binding group A streptococcal M-like protein PAM (P49054)
Plasminogen-binding group A streptococcal M-like protein PAM (UniProt P49054): 18 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P49054
- Protein
- Plasminogen-binding group A streptococcal M-like protein PAM
- Experimental structures
- 18
- Predicted models
- 1
- Pockets
- 3 · 2 records with a druggable one
Structures
19 records of P49054 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1I5K | Structure and binding determinants of the recombinant kringle-2 domain of human plasminogen to an… | x-ray diffraction | C, D | — | — |
| 1I5K | Structure and binding determinants of the recombinant kringle-2 domain of human plasminogen to an… | x-ray diffraction | C, D | — | — |
| 2DOI | The X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound to a peptide… | x-ray diffraction | C, B | — | — |
| 2DOI | The X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound to a peptide… | x-ray diffraction | C, B | — | — |
| 6OG4 | plasminogen binding group A streptococcal M protein | x-ray diffraction | C | — | 1 (best 0.39) |
| 6OG4 | Plasminogen binding group a streptococcal M protein | x-ray diffraction | C | — | — |
| 6OKW | Solution structure of VEK50 | solution nmr | A | — | — |
| 6OKW | Solution structure of VEK50 | solution nmr | A | — | — |
| 6OKX | Solution structure of VEK50RH1/AA | solution nmr | A | — | — |
| 6OKX | Solution structure of VEK50RH1/AA | solution nmr | A | — | — |
| 6OKY | Solution structure of truncated peptide from PAMap53 | solution nmr | A | — | — |
| 6OKY | Solution structure of truncated peptide from PAMAP53 | solution nmr | A | — | — |
| 6OQ9 | Solution structure of VEK50 in the bound form with plasminogen kringle 2 | solution nmr | A | — | — |
| 6OQ9 | Solution structure of VEK50 in the bound form with plasminogen kringle 2 | solution nmr | A | — | — |
| 6OQJ | Solution structure of the complex of mutant VEK50[RH1/AA] and plasminogen kringle 2 | solution nmr | B | — | 1 (best 0.63) |
| 6OQJ | Solution structure of the complex of mutant VEK50[RH1/AA] and plasminogen kringle 2 | solution nmr | B | — | — |
| 6OQK | Solution structure of the complex of mutant VEK50[RH2/AA] and plasminogen kringle 2 | solution nmr | B | — | 1 (best 0.50) |
| 6OQK | Solution structure of the complex of mutant VEK50[RH2/AA] and plasminogen kringle 2 | solution nmr | B | — | — |
| P49054 | AlphaFold monomer V2.0 prediction for plasminogen-binding group a streptococcal M-like protein pam… | predicted | A | — | — |
Experiment against prediction
- 6OG4 chain C against the predicted model P49054: TM-score 0.95, RMSD 0.37 Å
- 6OG4 chain C against the predicted model P49054: TM-score 0.95, RMSD 0.37 Å
- 1I5K chain C against the predicted model P49054: TM-score 0.79, RMSD 0.44 Å
- 1I5K chain C against the predicted model P49054: TM-score 0.79, RMSD 0.44 Å
- 2DOI chain B against the predicted model P49054: TM-score 0.76, RMSD 1.30 Å
- 2DOI chain B against the predicted model P49054: TM-score 0.76, RMSD 1.30 Å
- 2DOI chain C against the predicted model P49054: TM-score 0.70, RMSD 1.29 Å
- 2DOI chain C against the predicted model P49054: TM-score 0.70, RMSD 1.29 Å
- 6OQ9 chain A against the predicted model P49054: TM-score 0.55, RMSD 2.14 Å
- 6OQ9 chain A against the predicted model P49054: TM-score 0.55, RMSD 2.14 Å
Elsewhere
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