UniProt P48357
Leptin receptor (P48357)
Leptin receptor (UniProt P48357): 8 experimental structures on GenesisL1, 2 ligands bound, 47 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P48357
- Protein
- Leptin receptor
- Experimental structures
- 8
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 47 · 3 records with a druggable one
Structures
8 records of P48357 in the MolNFT archive: 8 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3V6O | Leptin Receptor-antibody complex | x-ray diffraction | A, B | — | — |
| 3V6O | Leptin receptor-antibody complex | x-ray diffraction | A, B | — | — |
| 6E2P | Structure of human JAK2 FERM/SH2 in complex with Leptin Receptor | x-ray diffraction | C, D | — | — |
| 6E2P | Structure of human JAK2 FERM/SH2 in complex with leptin receptor | x-ray diffraction | C, D | — | — |
| 8AVE | Human leptin in complex with the human LEP-R ectodomain fused to a C-terminal trimeric isoleucine… | electron microscopy | B, D | — | 12 (best 0.57) |
| 8X80 | Structure of leptin-LepR trimer with a small gap | electron microscopy | A, B, C | NAG, FUC | 17 (best 0.73) |
| 8X85 | Structure of leptin-LepR dimer | electron microscopy | A, B | NAG, FUC | 18 (best 0.71) |
| P48357 | AlphaFold monomer V2.0 prediction for leptin receptor (P48357) | — | — | — |
Ligands
Elsewhere
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