UniProt P48011
DNA-directed RNA polymerases I, II, and III subunit RPABC4 (P48011)
DNA-directed RNA polymerases I, II, and III subunit RPABC4 (UniProt P48011): 10 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 8 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P48011
- Protein
- DNA-directed RNA polymerases I, II, and III subunit RPABC4
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 8 · 3 records with a druggable one
Structures
11 records of P48011 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3H0G | RNA Polymerase II from Schizosaccharomyces pombe | x-ray diffraction | L, X | — | — |
| 3H0G | RNA polymerase II from schizosaccharomyces pombe | x-ray diffraction | L, X | — | — |
| 5U0S | Cryo-EM structure of the Mediator-RNAPII complex | electron microscopy | l | — | — |
| 5U0S | Cryo-EM structure of the mediator-rnapii complex | electron microscopy | l | — | — |
| 7AOC | Schizosaccharomyces pombe RNA polymerase I (monomer) | electron microscopy | L | ZN | 3 (best 0.80) |
| 7AOC | Schizosaccharomyces pombe RNA polymerase I (monomer) | electron microscopy | L | ZN | — |
| 7AOD | Schizosaccharomyces pombe RNA polymerase I (dimer) | electron microscopy | L, X | ZN | 2 (best 0.82) |
| 7AOD | Schizosaccharomyces pombe RNA polymerase I (dimer) | electron microscopy | L, X | ZN | — |
| 7AOE | Schizosaccharomyces pombe RNA polymerase I (elongation complex) | electron microscopy | L | ZN | 3 (best 0.78) |
| 7AOE | Schizosaccharomyces pombe RNA polymerase I (elongation complex) | electron microscopy | L | ZN | — |
| P48011 | AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerases I, II, and III subunit RPABC4… | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 6 records
Experiment against prediction
- 7AOC chain L against the predicted model P48011: TM-score 0.76, RMSD 1.86 Å
- 7AOC chain L against the predicted model P48011: TM-score 0.76, RMSD 1.86 Å
- 7AOD chain L against the predicted model P48011: TM-score 0.76, RMSD 2.06 Å
- 7AOD chain L against the predicted model P48011: TM-score 0.76, RMSD 2.06 Å
- 7AOD chain X against the predicted model P48011: TM-score 0.76, RMSD 2.06 Å
- 7AOE chain L against the predicted model P48011: TM-score 0.76, RMSD 2.02 Å
- 7AOE chain L against the predicted model P48011: TM-score 0.76, RMSD 2.02 Å
- 3H0G chain L against the predicted model P48011: TM-score 0.73, RMSD 1.65 Å
- 3H0G chain L against the predicted model P48011: TM-score 0.73, RMSD 1.65 Å
- 5U0S chain l against the predicted model P48011: TM-score 0.73, RMSD 1.65 Å
Elsewhere
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