UniProt P48004
Proteasome subunit alpha type-7 (P48004)
Proteasome subunit alpha type-7 (UniProt P48004), EC 3.4.25.1: 10 experimental structures and 1 predicted model on GenesisL1, 17 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P48004
- Protein
- Proteasome subunit alpha type-7
- EC
- 3.4.25.1
- Experimental structures
- 10
- Predicted models
- 1
- Pockets
- 17 · 5 records with a druggable one
Structures
11 records of P48004 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6EPC | Ground state 26S proteasome (GS2) | electron microscopy | D | — | 3 (best 0.78) |
| 6EPC | Ground state 26S proteasome (GS2) | electron microscopy | D | — | — |
| 6EPD | Substrate processing state 26S proteasome (SPS1) | electron microscopy | D | — | 3 (best 0.81) |
| 6EPD | Substrate processing state 26S proteasome (SPS1) | electron microscopy | D | — | — |
| 6EPE | Substrate processing state 26S proteasome (SPS2) | electron microscopy | D | — | 2 (best 0.76) |
| 6EPE | Substrate processing state 26S proteasome (SPS2) | electron microscopy | D | — | — |
| 6EPF | Ground state 26S proteasome (GS1) | electron microscopy | D | — | 2 (best 0.85) |
| 6EPF | Ground state 26S proteasome (GS1) | electron microscopy | D | — | — |
| 6TU3 | Rat 20S proteasome | electron microscopy | D, R | — | 4 (best 0.78) |
| 6TU3 | Rat 20S proteasome | electron microscopy | D, R | — | — |
| P48004 | AlphaFold monomer V2.0 prediction for proteasome subunit alpha type-7 (P48004) | predicted | A | — | 3 (best 0.39) |
Experiment against prediction
- 6TU3 chain R against the predicted model P48004: TM-score 0.96, RMSD 1.20 Å
- 6TU3 chain D against the predicted model P48004: TM-score 0.96, RMSD 1.20 Å
- 6TU3 chain D against the predicted model P48004: TM-score 0.96, RMSD 1.20 Å
- 6EPF chain D against the predicted model P48004: TM-score 0.89, RMSD 2.14 Å
- 6EPF chain D against the predicted model P48004: TM-score 0.89, RMSD 2.14 Å
- 6EPE chain D against the predicted model P48004: TM-score 0.89, RMSD 2.48 Å
- 6EPE chain D against the predicted model P48004: TM-score 0.89, RMSD 2.48 Å
- 6EPC chain D against the predicted model P48004: TM-score 0.86, RMSD 2.51 Å
- 6EPC chain D against the predicted model P48004: TM-score 0.86, RMSD 2.51 Å
- 6EPD chain D against the predicted model P48004: TM-score 0.84, RMSD 2.76 Å
Elsewhere
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