UniProt P47112
Cell division cycle protein CDT1 (P47112)
Cell division cycle protein CDT1 (UniProt P47112): 15 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 29 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P47112
- Protein
- Cell division cycle protein CDT1
- Experimental structures
- 15
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 29 · 5 records with a druggable one
Structures
16 records of P47112 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5ME9 | Crystal structure of yeast Cdt1 (N terminal and middle domain), form 1. | x-ray diffraction | A, B, C | SO4 | 18 (best 0.69) |
| 5ME9 | Crystal structure of yeast CDT1 (N terminal and middle domain), form 1. | x-ray diffraction | A, B, C | SO4 | — |
| 5MEA | Crystal structure of yeast Cdt1 (N terminal and middle domain), form 2. | x-ray diffraction | A | SO4 | 3 (best 0.55) |
| 5MEA | Crystal structure of yeast CDT1 (N terminal and middle domain), form 2. | x-ray diffraction | A | SO4 | — |
| 5MEB | Crystal structure of yeast Cdt1 C-terminal domain | x-ray diffraction | A, B | SO4 | 2 (best 0.40) |
| 5MEB | Crystal structure of yeast CDT1 C-terminal domain | x-ray diffraction | A, B | SO4 | — |
| 5MEC | Crystal structure of yeast CDT1 middle domain (residues 294-433) | x-ray diffraction | A | — | — |
| 5V8F | Structural basis of MCM2-7 replicative helicase loading by ORC-Cdc6 and Cdt1 | electron microscopy | 8 | — | 1 (best 0.80) |
| 5V8F | Structural basis of MCM2-7 replicative helicase loading by orc-CDC6 and CDT1 | electron microscopy | 8 | — | — |
| 5XF8 | Cryo-EM structure of the Cdt1-MCM2-7 complex in AMPPNP state | electron microscopy | C | — | 4 (best 0.81) |
| 5XF8 | Cryo-EM structure of the CDT1-MCM2-7 complex in amppnp state | electron microscopy | C | — | — |
| 6WGG | Atomic model of pre-insertion mutant OCCM-DNA complex(ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation) | electron microscopy | 8 | — | 1 (best 0.79) |
| 6WGG | Atomic model of pre-insertion mutant occm-DNA COMPLEX(ORC-CDC6-CDT1- MCM2-7 with MCM6 whd… | electron microscopy | 8 | — | — |
| 6WGI | Atomic model of the mutant OCCM (ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation) loaded on DNA at… | electron microscopy | L | — | — |
| 6WGI | Atomic model of the mutant occm (orc-CDC6-CDT1-MCM2-7 with MCM6 whd truncation) loaded on DNA at… | electron microscopy | L | — | — |
| P47112 | AlphaFold monomer V2.0 prediction for cell division cycle protein CDT1 (P47112) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 6 records
Experiment against prediction
- 5ME9 chain B against the predicted model P47112: TM-score 0.99, RMSD 0.81 Å
- 5ME9 chain B against the predicted model P47112: TM-score 0.99, RMSD 0.81 Å
- 5ME9 chain A against the predicted model P47112: TM-score 0.98, RMSD 1.02 Å
- 5ME9 chain A against the predicted model P47112: TM-score 0.98, RMSD 1.02 Å
- 5MEA chain A against the predicted model P47112: TM-score 0.98, RMSD 1.11 Å
- 5MEA chain A against the predicted model P47112: TM-score 0.98, RMSD 1.11 Å
- 5ME9 chain C against the predicted model P47112: TM-score 0.96, RMSD 1.39 Å
- 5ME9 chain C against the predicted model P47112: TM-score 0.96, RMSD 1.39 Å
- 5MEC chain A against the predicted model P47112: TM-score 0.95, RMSD 1.25 Å
- 6WGI chain L against the predicted model P47112: TM-score 0.85, RMSD 3.02 Å
Elsewhere
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