UniProt P46799
DNA topoisomerase 1 (P46799)
DNA topoisomerase 1 (UniProt P46799): 4 experimental structures and 1 predicted model on GenesisL1, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P46799
- Protein
- DNA topoisomerase 1
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 6 · 1 record with a druggable one
Structures
5 records of P46799 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2GAI | Structure of Full Length Topoisomerase I from Thermotoga maritima in triclinic crystal form | x-ray diffraction | A, B | — | — |
| 2GAI | Structure of full length topoisomerase I from thermotoga maritima in triclinic crystal form | x-ray diffraction | A, B | — | — |
| 2GAJ | Structure of Full Length Topoisomerase I from Thermotoga maritima in monoclinic crystal form | x-ray diffraction | A, B | — | — |
| 2GAJ | Structure of full length topoisomerase I from thermotoga maritima in monoclinic crystal form | x-ray diffraction | A, B | — | — |
| P46799 | AlphaFold monomer V2.0 prediction for DNA topoisomerase 1 (P46799) | predicted | A | — | 6 (best 0.71) |
Experiment against prediction
- 2GAI chain A against the predicted model P46799: TM-score 1.00, RMSD 0.61 Å
- 2GAI chain A against the predicted model P46799: TM-score 1.00, RMSD 0.61 Å
- 2GAJ chain A against the predicted model P46799: TM-score 0.99, RMSD 0.66 Å
- 2GAJ chain A against the predicted model P46799: TM-score 0.99, RMSD 0.66 Å
Elsewhere
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