UniProt P45984
Mitogen-activated protein kinase 9 (P45984)
Mitogen-activated protein kinase 9 (UniProt P45984), EC 2.7.11.24: 7 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- P45984
- Protein
- Mitogen-activated protein kinase 9
- EC
- 2.7.11.24
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 5 · 1 record with a druggable one
Structures
8 records of P45984 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3E7O | Crystal Structure of JNK2 | x-ray diffraction | A, B | — | — |
| 3E7O | Crystal structure of JNK2 | x-ray diffraction | A, B | — | — |
| 3NPC | Crystal structure of JNK2 complexed with BIRB796 | x-ray diffraction | A, B | — | — |
| 3NPC | Crystal structure of JNK2 complexed with BIRB796 | x-ray diffraction | A, B | — | — |
| 7CML | The crystal structure of human JNK2 from biortus. | x-ray diffraction | A, B | — | — |
| 7N8T | Crystal structure of AMP-bound human JNK2 | x-ray diffraction | A | AMP | — |
| 8ELC | Human JNK2 bound to covalent inhibitor YL2056 | x-ray diffraction | A | Y56 | 5 (best 0.76) |
| P45984 | AlphaFold monomer V2.0 prediction for mitogen-activated protein kinase 9 (P45984) | predicted | A | — | — |
Ligands
Experiment against prediction
- 3E7O chain B against the predicted model P45984: TM-score 0.98, RMSD 1.06 Å
- 3E7O chain B against the predicted model P45984: TM-score 0.98, RMSD 1.06 Å
- 3E7O chain A against the predicted model P45984: TM-score 0.95, RMSD 1.61 Å
- 3E7O chain A against the predicted model P45984: TM-score 0.95, RMSD 1.61 Å
- 7N8T chain A against the predicted model P45984: TM-score 0.94, RMSD 1.97 Å
- 8ELC chain A against the predicted model P45984: TM-score 0.93, RMSD 1.92 Å
- 3NPC chain A against the predicted model P45984: TM-score 0.90, RMSD 2.20 Å
- 3NPC chain A against the predicted model P45984: TM-score 0.90, RMSD 2.20 Å
- 3NPC chain B against the predicted model P45984: TM-score 0.89, RMSD 2.22 Å
- 3NPC chain B against the predicted model P45984: TM-score 0.89, RMSD 2.22 Å
Elsewhere
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