UniProt P45379
Troponin T, cardiac muscle (P45379)
Troponin T, cardiac muscle (UniProt P45379): 11 experimental structures and 1 predicted model on GenesisL1, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P45379
- Protein
- Troponin T, cardiac muscle
- Experimental structures
- 11
- Predicted models
- 1
- Pockets
- 6 · 0 records with a druggable one
Structures
12 records of P45379 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1J1D | Crystal structure of the 46kDa domain of human cardiac troponin in the Ca2+ saturated form | x-ray diffraction | B, E | — | — |
| 1J1D | Crystal structure of the 46KDA domain of human cardiac troponin in the CA2+ saturated form | x-ray diffraction | B, E | — | — |
| 1J1E | Crystal structure of the 52kDa domain of human cardiac troponin in the Ca2+ saturated form | x-ray diffraction | B, E | — | — |
| 1J1E | Crystal structure of the 52KDA domain of human cardiac troponin in the CA2+ saturated form | x-ray diffraction | B, E | — | — |
| 4Y99 | Core domain of human cardiac troponin | x-ray diffraction | B | — | — |
| 4Y99 | Core domain of human cardiac troponin | x-ray diffraction | B | — | — |
| 6KN7 | Structure of human cardiac thin filament in the calcium free state | electron microscopy | T, a | — | — |
| 6KN7 | Structure of human cardiac thin filament in the calcium free state | electron microscopy | T, a | — | — |
| 6KN8 | Structure of human cardiac thin filament in the calcium bound state | electron microscopy | T, a | — | — |
| 7UTI | Alternative modeling of tropomyosin in human cardiac thin filament in the calcium bound state | electron microscopy | X, Y, c, d | — | — |
| 8FMO | Complex structure of K210 deletion Troponin complex with risedronate | x-ray diffraction | B, E | — | 6 (best 0.46) |
| P45379 | AlphaFold monomer V2.0 prediction for troponin T, cardiac muscle (P45379) | predicted | A | — | — |
Experiment against prediction
- 7UTI chain X against the predicted model P45379: TM-score 0.82, RMSD 1.57 Å
- 4Y99 chain B against the predicted model P45379: TM-score 0.79, RMSD 1.50 Å
- 4Y99 chain B against the predicted model P45379: TM-score 0.79, RMSD 1.50 Å
- 8FMO chain B against the predicted model P45379: TM-score 0.76, RMSD 1.40 Å
- 7UTI chain Y against the predicted model P45379: TM-score 0.76, RMSD 1.97 Å
- 8FMO chain E against the predicted model P45379: TM-score 0.75, RMSD 0.96 Å
- 1J1E chain E against the predicted model P45379: TM-score 0.74, RMSD 1.36 Å
- 1J1E chain E against the predicted model P45379: TM-score 0.74, RMSD 1.36 Å
- 1J1D chain E against the predicted model P45379: TM-score 0.71, RMSD 1.40 Å
- 1J1D chain E against the predicted model P45379: TM-score 0.71, RMSD 1.40 Å
Elsewhere
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