UniProt P43618
Inner kinetochore subunit CNN1 (P43618)
Inner kinetochore subunit CNN1 (UniProt P43618): 6 experimental structures and 1 predicted model on GenesisL1, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P43618
- Protein
- Inner kinetochore subunit CNN1
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 4 · 1 record with a druggable one
Structures
7 records of P43618 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4GEQ | Crystal structure of the Spc24-Spc25/Cnn1 binding interface | x-ray diffraction | E, F | — | — |
| 4GEQ | Crystal structure of the SPC24-SPC25/CNN1 binding interface | x-ray diffraction | E, F | — | — |
| 6WUC | The yeast Ctf3 complex with Cnn1-Wip1 | electron microscopy | T | — | 4 (best 0.61) |
| 6WUC | The yeast CTF3 complex with CNN1-WIP1 | electron microscopy | T | — | — |
| 6YPC | Crystal structure of the kinetochore subunits H/I/K/T/W penta-complex from S. cerevisiae at 2.9… | x-ray diffraction | T | — | — |
| 8OW1 | Cryo-EM structure of the yeast Inner kinetochore bound to a CENP-A nucleosome. | electron microscopy | T, TT | — | — |
| P43618 | AlphaFold monomer V2.0 prediction for inner kinetochore subunit CNN1 (P43618) | predicted | A | — | — |
Experiment against prediction
- 6WUC chain T against the predicted model P43618: TM-score 0.77, RMSD 2.00 Å
- 6WUC chain T against the predicted model P43618: TM-score 0.77, RMSD 2.00 Å
- 4GEQ chain E against the predicted model P43618: TM-score 0.76, RMSD 0.38 Å
- 4GEQ chain E against the predicted model P43618: TM-score 0.76, RMSD 0.38 Å
- 6YPC chain T against the predicted model P43618: TM-score 0.70, RMSD 2.62 Å
- 8OW1 chain T against the predicted model P43618: TM-score 0.70, RMSD 2.68 Å
- 8OW1 chain TT against the predicted model P43618: TM-score 0.68, RMSD 2.78 Å
- 4GEQ chain F against the predicted model P43618: TM-score 0.66, RMSD 0.47 Å
- 4GEQ chain F against the predicted model P43618: TM-score 0.66, RMSD 0.47 Å
Elsewhere
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