UniProt P43431
Interleukin-12 subunit alpha (P43431)
Interleukin-12 subunit alpha (UniProt P43431): 4 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 18 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P43431
- Protein
- Interleukin-12 subunit alpha
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 18 · 4 records with a druggable one
Structures
5 records of P43431 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8CR6 | mouse Interleukin-12 | x-ray diffraction | B | NAG | 3 (best 0.69) |
| 8ODZ | Cryo-EM structure of a pre-dimerized murine IL-12 complete extracellular signaling complex (Class… | electron microscopy | A | — | 4 (best 0.64) |
| 8OE0 | Cryo-EM structure of a pre-dimerized murine IL-12 complete extracellular signaling complex (Class… | electron microscopy | A | — | 6 (best 0.67) |
| 8PB1 | Cryo-EM structure of a pre-dimerized murine IL-12 complete extracellular signaling complex (Class… | electron microscopy | A | — | 5 (best 0.64) |
| P43431 | AlphaFold monomer V2.0 prediction for interleukin-12 subunit alpha (P43431) | predicted | A | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 1 record
Experiment against prediction
- 8ODZ chain A against the predicted model P43431: TM-score 0.95, RMSD 1.19 Å
- 8CR6 chain B against the predicted model P43431: TM-score 0.94, RMSD 1.56 Å
- 8PB1 chain A against the predicted model P43431: TM-score 0.94, RMSD 1.43 Å
- 8OE0 chain A against the predicted model P43431: TM-score 0.93, RMSD 1.41 Å
Elsewhere
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