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UniProt P43403

Peptide from Tyrosine-protein kinase ZAP-70 (P43403)

Peptide from Tyrosine-protein kinase ZAP-70 (UniProt P43403), EC 2.7.10.2: 24 experimental structures on GenesisL1, 2 ligands bound, 1 pocket. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
P43403
Protein
Peptide from Tyrosine-protein kinase ZAP-70
EC
2.7.10.2
Experimental structures
24
Predicted models
0
Ligands
2
Pockets
1 · 0 records with a druggable one

Structures

24 records of P43403 in the MolNFT archive: 24 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
1M61Crystal structure of the apo SH2 domains of ZAP-70x-ray diffractionA——
1M61Crystal structure of the apo SH2 domains of zap-70x-ray diffractionA——
1U59Crystal Structure of the ZAP-70 Kinase Domain in Complex with Staurosporinex-ray diffractionA——
1U59Crystal structure of the zap-70 kinase domain in complex with staurosporinex-ray diffractionA——
2OQ1Tandem SH2 domains of ZAP-70 with 19-mer zeta1 peptidex-ray diffractionA——
2OQ1Tandem SH2 domains of zap-70 with 19-mer ZETA1 peptidex-ray diffractionA——
2OZOAutoinhibited intact human ZAP-70x-ray diffractionA——
2OZOAutoinhibited intact human zap-70x-ray diffractionA——
2Y1NStructure of c-Cbl-ZAP-70 peptide complexx-ray diffractionB, D——
2Y1NStructure of C-cbl-zap-70 peptide complexx-ray diffractionB, D——
3ZNIStructure of phosphoTyr363-Cbl-b - UbcH5B-Ub - ZAP-70 peptide complexx-ray diffractionB, F, J, N——
3ZNIStructure of PHOSPHOTYR363-cbl-B - UBCH5B-ub - zap-70 peptide complexx-ray diffractionB, F, J, N——
4A4BStructure of modified phosphoTyr371-c-Cbl-UbcH5B-ZAP-70 complexx-ray diffractionB——
4A4BStructure of modified PHOSPHOTYR371-C-cbl-UBCH5B-zap-70 complexx-ray diffractionB——
4A4CStructure of phosphoTyr371-c-Cbl-UbcH5B-ZAP-70 complexx-ray diffractionB——
4A4CStructure of PHOSPHOTYR371-C-cbl-UBCH5B-zap-70 complexx-ray diffractionB——
4K2RStructural basis for activation of ZAP-70 by phosphorylation of the SH2-kinase linkerx-ray diffractionA——
4K2RStructural basis for activation of zap-70 by phosphorylation of the SH2-kinase linkerx-ray diffractionA——
4XZ0ZAP-70-tSH2:compound-A complexx-ray diffractionA4N5, SO41 (best 0.44)
4XZ0Zap-70-TSH2:COMPOUND-a complexx-ray diffractionA——
4XZ1ZAP-70-tSH2:Compound-B adductx-ray diffractionA——
4XZ1Zap-70-TSH2:COMPOUND-B adductx-ray diffractionA——
7SIYcCBL TKB domain in complex with pZAP70 peptidex-ray diffractionZ——
P43403AlphaFold monomer V2.0 prediction for tyrosine-protein kinase zap-70 (P43403)———

Ligands

  • 4N5 · 1-(3-{5-[(3-chlorobenzyl)sulfonyl]-1H-tetrazol-1-yl}phenyl)ethanone · in 1 record
  • SO4 · Sulfate ion · in 1 record

Elsewhere

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