UniProt P43354
Nuclear receptor subfamily 4 group A member 2 (P43354)
Nuclear receptor subfamily 4 group A member 2 (UniProt P43354): 11 experimental structures on GenesisL1, 9 ligands bound, 49 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P43354
- Protein
- Nuclear receptor subfamily 4 group A member 2
- Experimental structures
- 11
- Predicted models
- 0
- Ligands
- 9
- Pockets
- 49 · 5 records with a druggable one
Structures
11 records of P43354 in the MolNFT archive: 11 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1OVL | Crystal Structure of Nurr1 LBD | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1OVL | Crystal structure of NURR1 lbd | x-ray diffraction | A, B, C, D, E, F | — | — |
| 5Y41 | Crystal Structure of LIGAND-BOUND NURR1-LBD | x-ray diffraction | A, B | RPG, CL, MG | 6 (best 0.62) |
| 5Y41 | Crystal structure of ligand-bound NURR1-lbd | x-ray diffraction | A, B | RPG, CL, MG | — |
| 5YD6 | Crystal structure of PG-bound Nurr1-LBD | x-ray diffraction | A, B, C, D | 8SU, MG | 13 (best 0.68) |
| 5YD6 | Crystal structure of pg-bound NURR1-lbd | x-ray diffraction | A, B, C, D | 8SU, MG | — |
| 6DDA | Nurr1 Covalently Modified by a Dopamine Metabolite | x-ray diffraction | B, A, C | K, G7J, BR | 6 (best 0.66) |
| 6DDA | NURR1 covalently modified by a dopamine metabolite | x-ray diffraction | B, A, C | K, G7J, BR | — |
| 7WNH | Crystal structure of Nurr1 binding to NBRE | x-ray diffraction | A, B, C, D | ZN | 20 (best 0.79) |
| 8CYO | Nurr1 Covalently Bound to a Synthetic Ligand, 10.25, via a Disulfide Bond | x-ray diffraction | B, A | CL, OBJ | 4 (best 0.61) |
| P43354 | AlphaFold monomer V2.0 prediction for nuclear receptor subfamily 4 group a member 2 (P43354) | — | — | — |
Ligands
- MG · Magnesium ion · in 4 records
- CL · Chloride ion · in 3 records
- 8SU · (~{Z})-7-[(1~{R},5~{S})-2-oxidanylidene-5-[(~{E}, 3~{S})-3-oxidanyloct-1-enyl]cyclopent-3-en-1-yl]hept-5-enoic acid · in 2 records
- BR · Bromide ion · in 2 records
- G7J · 5-hydroxy-1,2-dihydro-6H-indol-6-one · in 2 records
- K · Potassium ion · in 2 records
- RPG · (13E,15S)-15-hydroxy-9-oxoprosta-10,13-dien-1-oic acid · in 2 records
- OBJ · 2-(3,4-dichlorophenoxy)-N-(2-sulfanylethyl)acetamide · in 1 record
- ZN · Zinc ion · in 1 record
Elsewhere
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