UniProt P43250
G protein-coupled receptor kinase 6 (P43250)
G protein-coupled receptor kinase 6 (UniProt P43250): 6 experimental structures and 1 predicted model on GenesisL1, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P43250
- Protein
- G protein-coupled receptor kinase 6
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 7 · 1 record with a druggable one
Structures
7 records of P43250 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2ACX | Crystal Structure of G protein coupled receptor kinase 6 bound to AMPPNP | x-ray diffraction | A, B | — | — |
| 2ACX | Crystal structure of G protein coupled receptor kinase 6 bound to amppnp | x-ray diffraction | A, B | — | — |
| 3NYN | Crystal Structure of G Protein-Coupled Receptor Kinase 6 in Complex with Sangivamycin | x-ray diffraction | A, B | — | — |
| 3NYN | Crystal structure of G protein-coupled receptor kinase 6 in complex with sangivamycin | x-ray diffraction | A, B | — | — |
| 3NYO | Crystal Structure of G Protein-Coupled Receptor Kinase 6 in Complex with AMP | x-ray diffraction | A, B | — | — |
| 3NYO | Crystal structure of G protein-coupled receptor kinase 6 in complex with AMP | x-ray diffraction | A, B | — | — |
| P43250 | AlphaFold monomer V2.0 prediction for G protein-coupled receptor kinase 6 (P43250) | predicted | A | — | 7 (best 0.73) |
Experiment against prediction
- 2ACX chain A against the predicted model P43250: TM-score 0.97, RMSD 1.58 Å
- 2ACX chain A against the predicted model P43250: TM-score 0.97, RMSD 1.58 Å
- 2ACX chain B against the predicted model P43250: TM-score 0.97, RMSD 1.56 Å
- 2ACX chain B against the predicted model P43250: TM-score 0.97, RMSD 1.56 Å
- 3NYO chain A against the predicted model P43250: TM-score 0.90, RMSD 2.17 Å
- 3NYO chain A against the predicted model P43250: TM-score 0.90, RMSD 2.17 Å
- 3NYN chain A against the predicted model P43250: TM-score 0.90, RMSD 2.19 Å
- 3NYN chain A against the predicted model P43250: TM-score 0.90, RMSD 2.19 Å
Elsewhere
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