UniProt P43132
COMPASS component BRE2 (P43132)
COMPASS component BRE2 (UniProt P43132): 5 experimental structures and 1 predicted model on GenesisL1, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P43132
- Protein
- COMPASS component BRE2
- Experimental structures
- 5
- Predicted models
- 1
- Pockets
- 5 · 1 record with a druggable one
Structures
6 records of P43132 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4RT4 | Crystal structure of Dpy30 complexed with Bre2 | x-ray diffraction | E | — | — |
| 4RT4 | Crystal structure of DPY30 complexed with BRE2 | x-ray diffraction | E | — | — |
| 6BX3 | Structure of histone H3k4 methyltransferase | electron microscopy | K | — | 5 (best 0.79) |
| 6BX3 | Structure of histone H3K4 methyltransferase | electron microscopy | K | — | — |
| 6VEN | Yeast compass in complex with a ubiquitinated nucleosome | electron microscopy | O | — | — |
| P43132 | AlphaFold monomer V2.0 prediction for compass component BRE2 (P43132) | predicted | A | — | — |
Experiment against prediction
- 6VEN chain O against the predicted model P43132: TM-score 0.97, RMSD 1.37 Å
- 6BX3 chain K against the predicted model P43132: TM-score 0.87, RMSD 2.26 Å
- 6BX3 chain K against the predicted model P43132: TM-score 0.87, RMSD 2.26 Å
- 4RT4 chain E against the predicted model P43132: TM-score 0.61, RMSD 0.53 Å
- 4RT4 chain E against the predicted model P43132: TM-score 0.61, RMSD 0.53 Å
Elsewhere
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