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UniProt P43119

Prostacyclin receptor (P43119)

Prostacyclin receptor (UniProt P43119): 2 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 16 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt
P43119
Protein
Prostacyclin receptor
Experimental structures
2
Predicted models
1
Ligands
2
Pockets
16 · 3 records with a druggable one

Structures

3 records of P43119 in the MolNFT archive: 2 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
8X79MRE-269 bound Prostacyclin Receptor G protein complexelectron microscopyRY9Q7 (best 0.87)
8X7ATreprostinil bound Prostacyclin Receptor G protein complexelectron microscopyRY9J4 (best 0.80)
P43119AlphaFold monomer V2.0 prediction for prostacyclin receptor (P43119)predictedA—5 (best 0.81)

Ligands

  • Y9J · Treprostinil · in 1 record
  • Y9Q · 2-[4-[(5,6-diphenylpyrazin-2-yl)-propan-2-yl-amino]butoxy]ethanoic acid · in 1 record

Experiment against prediction

Elsewhere

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