UniProt P43098
Fatty acid synthase subunit alpha (P43098)
Fatty acid synthase subunit alpha (UniProt P43098), EC 1.1.1.100, 2.3.1.41: 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 22 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P43098
- Protein
- Fatty acid synthase subunit alpha
- EC
- 1.1.1.100, 2.3.1.41, 2.3.1.86
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 22 · 2 records with a druggable one
Structures
5 records of P43098 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6U5V | Electron cryomicroscopy Structure of C. albicans FAS in the Apo state | electron microscopy | A | PNS | 10 (best 0.83) |
| 6U5V | Electron cryomicroscopy structure of C. albicans fas in the apo state | electron microscopy | A | PNS | — |
| 6U5W | Electron cryomicroscopy structure of C. albicans fas in the ks-stalled state | electron microscopy | A | NAP | — |
| 7TUI | Structure of C. albicans FAS in an inhibited state | electron microscopy | A | — | 12 (best 0.81) |
| P43098 | AlphaFold monomer V2.0 prediction for fatty acid synthase subunit alpha (P43098) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6U5W chain A against the predicted model P43098: TM-score 0.97, RMSD 2.37 Å
- 7TUI chain A against the predicted model P43098: TM-score 0.97, RMSD 2.58 Å
- 6U5V chain A against the predicted model P43098: TM-score 0.88, RMSD 2.62 Å
- 6U5V chain A against the predicted model P43098: TM-score 0.88, RMSD 2.62 Å
Elsewhere
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