UniProt P42701
Interleukin-12 receptor subunit beta-1 (P42701)
Interleukin-12 receptor subunit beta-1 (UniProt P42701): 5 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P42701
- Protein
- Interleukin-12 receptor subunit beta-1
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 4 · 2 records with a druggable one
Structures
6 records of P42701 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6WDP | Interleukin 12 receptor subunit beta-1 | x-ray diffraction | A | SO4 | — |
| 6WDP | Interleukin 12 receptor subunit beta-1 | x-ray diffraction | A | SO4 | — |
| 6WDQ | IL23/IL23R/IL12Rb1 signaling complex | x-ray diffraction | D | — | 2 (best 0.64) |
| 6WDQ | IL23/IL23R/IL12RB1 signaling complex | x-ray diffraction | D | — | — |
| 8ODX | Interleukin 12 receptor subunit beta-1 Fn domains in complex with antagonistic FAb4 fragment and… | x-ray diffraction | A | — | 2 (best 0.60) |
| P42701 | AlphaFold monomer V2.0 prediction for interleukin-12 receptor subunit beta-1 (P42701) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 2 records
Experiment against prediction
- 6WDQ chain D against the predicted model P42701: TM-score 0.93, RMSD 1.14 Å
- 6WDQ chain D against the predicted model P42701: TM-score 0.93, RMSD 1.14 Å
- 8ODX chain A against the predicted model P42701: TM-score 0.91, RMSD 2.06 Å
- 6WDP chain A against the predicted model P42701: TM-score 0.76, RMSD 3.44 Å
- 6WDP chain A against the predicted model P42701: TM-score 0.76, RMSD 3.44 Å
Elsewhere
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