UniProt P42582
Homeobox protein nkx-2.5 (P42582)
Homeobox protein nkx-2.5 (UniProt P42582): 1 experimental structure and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P42582
- Protein
- Homeobox protein nkx-2.5
- Experimental structures
- 1
- Predicted models
- 1
- Pockets
- 1 · 0 records with a druggable one
Structures
2 records of P42582 in the MolNFT archive: 1 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5FLV | Crystal structure of NKX2-5 and TBX5 bound to the nppa promoter region | x-ray diffraction | A, E, I, M | — | — |
| P42582 | AlphaFold monomer V2.0 prediction for homeobox protein nkx-2.5 (P42582) | predicted | A | — | 1 (best 0.30) |
Experiment against prediction
- 5FLV chain I against the predicted model P42582: TM-score 0.30, RMSD 3.49 Å
- 5FLV chain E against the predicted model P42582: TM-score 0.30, RMSD 3.63 Å
- 5FLV chain M against the predicted model P42582: TM-score 0.28, RMSD 4.66 Å
- 5FLV chain A against the predicted model P42582: TM-score 0.27, RMSD 3.65 Å
Elsewhere
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