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UniProt P42527

Myosin heavy chain kinase A (P42527)

Myosin heavy chain kinase A (UniProt P42527), EC 2.7.11.7: 23 experimental structures on GenesisL1, 5 ligands bound, 16 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
P42527
Protein
Myosin heavy chain kinase A
EC
2.7.11.7
Experimental structures
23
Predicted models
0
Ligands
5
Pockets
16 · 3 records with a druggable one

Structures

23 records of P42527 in the MolNFT archive: 23 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
3LKM1.6 Angstrom Crystal Structure of the Alpha-kinase Domain of Myosin Heavy Chain Kinase A Complex…x-ray diffractionA——
3LKM1.6 ångström crystal structure of the alpha-kinase domain of myosin heavy chain kinase a complex…x-ray diffractionA——
3LLACrystal Structure of the Alpha-kinase Domain of Myosin Heavy Chain Kinase A Complex with AMPPCPx-ray diffractionA, B——
3LLACrystal structure of the alpha-kinase domain of myosin heavy chain kinase a complex with amppcpx-ray diffractionA, B——
3LMHCrystal Structure of the Alpha-kinase Domain of Myosin Heavy Chain Kinase A Complex with ADPx-ray diffractionA, B——
3LMHCrystal structure of the alpha-kinase domain of myosin heavy chain kinase a complex with ADPx-ray diffractionA, B——
3LMICrystal Structure of the Inactive Alpha-kinase Domain of Myosin Heavy Chain Kinase A (D766A)…x-ray diffractionA, B, C, D——
3LMICrystal structure of the inactive alpha-kinase domain of myosin heavy chain kinase a (D766A)…x-ray diffractionA, B, C, D——
3PDTCrystal Structure of the C-terminal Truncated Alpha-Kinase Domain of Myosin Heavy chain Kinasex-ray diffractionA——
3PDTCrystal structure of the C-terminal truncated alpha-kinase domain of myosin heavy chain kinasex-ray diffractionA——
4ZMECrystal Structure of the Alpha-kinase Domain of Myosin-II Heavy Chain Kinase A in Complex with…x-ray diffractionA, BZN, ADN, PO45 (best 0.76)
4ZMECrystal structure of the alpha-kinase domain of myosin-II heavy chain kinase a in complex with…x-ray diffractionA, B——
4ZMFPhosphorylated Aspartate in the Crystal Structure of the Alpha-kinase domain of Myosin-II Heavy…x-ray diffractionA, BAMP, PO4, ZN5 (best 0.78)
4ZMFPhosphorylated aspartate in the crystal structure of the alpha-kinase domain of myosin-II heavy…x-ray diffractionA, B——
4ZS4Crystal Structure of the Inactive Alpha-kinase Domain of Myosin-II Heavy Chain Kinase A (D756A)…x-ray diffractionA, B——
4ZS4Crystal structure of the inactive alpha-kinase domain of myosin-II heavy chain kinase a (D756A)…x-ray diffractionA, B——
5DYJMysosin heavy chain kinase A catalytic domain mutant - D663Ax-ray diffractionA, BPO4, ZN, AMP6 (best 0.77)
5DYJMysosin heavy chain kinase a catalytic domain mutant - D663Ax-ray diffractionA, B——
5E4HCrystal Structure of Apoenzyme Alpha-kinase Domain of Myosin-II Heavy Chain Kinase Ax-ray diffractionA, B, C, D, E, F, G, HZN—
5E4HCrystal structure of apoenzyme alpha-kinase domain of myosin-II heavy chain kinase ax-ray diffractionA, B, C, D, E, F, G, H——
5E9ECrystal Structure of the Alpha-kinase Domain of Myosin-II Heavy Chain Kinase A in Complex with…x-ray diffractionA, BANP, ZN, PO4—
5E9ECrystal structure of the alpha-kinase domain of myosin-II heavy chain kinase a in complex with…x-ray diffractionA, B——
P42527AlphaFold monomer V2.0 prediction for myosin heavy chain kinase a (P42527)———

Ligands

  • ZN · Zinc ion · in 5 records
  • PO4 · Phosphate ion · in 4 records
  • AMP · Adenosine monophosphate · in 2 records
  • ADN · Adenosine · in 1 record
  • ANP · Phosphoaminophosphonic acid-adenylate ester · in 1 record

Elsewhere

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