UniProt P42356
Phosphatidylinositol 4-kinase alpha (P42356)
Phosphatidylinositol 4-kinase alpha (UniProt P42356), EC 2.7.1.67: 5 experimental structures on GenesisL1, 1 ligand bound, 30 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P42356
- Protein
- Phosphatidylinositol 4-kinase alpha
- EC
- 2.7.1.67
- Experimental structures
- 5
- Predicted models
- 0
- Ligands
- 1
- Pockets
- 30 · 2 records with a druggable one
Structures
5 records of P42356 in the MolNFT archive: 5 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6BQ1 | Human PI4KIIIa lipid kinase complex | electron microscopy | A, E | E4S | — |
| 6BQ1 | Human PI4KIIIA lipid kinase complex | electron microscopy | A, E | E4S | — |
| 9B9G | Structure of the PI4KA complex bound to Calcineurin | electron microscopy | A, B | — | 14 (best 0.85) |
| 9BAX | PI4KA complex bound to C-terminus of EFR3A | electron microscopy | B, A | — | 16 (best 0.87) |
| P42356 | AlphaFold monomer V2.0 prediction for phosphatidylinositol 4-kinase alpha (P42356) | — | — | — |
Ligands
- E4S · 5-{2-amino-1-[4-(morpholin-4-yl)phenyl]-1H-benzimidazol-6-yl}-N-(2-fluorophenyl)-2-methoxypyridine-3-sulfonamide · in 2 records
Elsewhere
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