UniProt P42337
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (P42337)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (UniProt P42337): 2 experimental structures and 1 predicted model on GenesisL1, 13 pockets. Binding sites, druggability and experiment against…
- UniProt
- P42337
- Protein
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
- Experimental structures
- 2
- Predicted models
- 1
- Pockets
- 13 · 1 record with a druggable one
Structures
3 records of P42337 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4A55 | Crystal structure of p110alpha in complex with iSH2 of p85alpha and the inhibitor PIK-108 | x-ray diffraction | A | — | — |
| 4A55 | Crystal structure of P110ALPHA in complex with ISH2 of P85ALPHA and the inhibitor pik-108 | x-ray diffraction | A | — | — |
| P42337 | AlphaFold monomer V2.0 prediction for phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic… | predicted | A | — | 13 (best 0.85) |
Experiment against prediction
- 4A55 chain A against the predicted model P42337: TM-score 0.98, RMSD 1.75 Å
- 4A55 chain A against the predicted model P42337: TM-score 0.98, RMSD 1.75 Å
Elsewhere
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