UniProt P42285
Exosome RNA helicase MTR4 (P42285)
Exosome RNA helicase MTR4 (UniProt P42285), EC 3.6.4.13: 18 experimental structures on GenesisL1, 6 ligands bound, 51 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P42285
- Protein
- Exosome RNA helicase MTR4
- EC
- 3.6.4.13
- Experimental structures
- 18
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 51 · 6 records with a druggable one
Structures
18 records of P42285 in the MolNFT archive: 18 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6C90 | Human Mtr4 helicase in complex with ZCCHC8-CTD | x-ray diffraction | A | ADP, MG | 6 (best 0.84) |
| 6C90 | Human MTR4 helicase in complex with ZCCHC8-ctd | x-ray diffraction | A | ADP, MG | — |
| 6D6Q | Human nuclear exosome-MTR4 RNA complex - overall reconstruction | electron microscopy | M | ANP | 4 (best 0.84) |
| 6D6Q | Human nuclear exosome-MTR4 RNA complex - overall reconstruction | electron microscopy | M | ANP | — |
| 6D6R | Human nuclear exosome-MTR4 RNA complex - composite MAP after focused reconstruction | electron microscopy | M | ANP | — |
| 6IEG | Crystal structure of human MTR4 | x-ray diffraction | B, A | ADP, MG | — |
| 6IEG | Crystal structure of human MTR4 | x-ray diffraction | B, A | ADP, MG | — |
| 6IEH | Crystal structures of the hMTR4-NRDE2 complex | x-ray diffraction | B | CL, ATP | — |
| 6IEH | Crystal structures of the HMTR4-NRDE2 complex | x-ray diffraction | B | CL, ATP | — |
| 6RO1 | X-ray crystal structure of the MTR4 NVL complex | x-ray diffraction | A | SO4, ADP, CL | 7 (best 0.77) |
| 6RO1 | X-ray crystal structure of the MTR4 nvl complex | x-ray diffraction | A | SO4, ADP, CL | — |
| 7S7B | Human Nuclear exosome targeting (NEXT) complex homodimer bound to RNA (substrate 1) | electron microscopy | A, E | — | — |
| 7S7B | Human nuclear exosome targeting (next) complex homodimer bound to RNA (substrate 1) | electron microscopy | A, E | — | — |
| 7S7C | Human nuclear exosome targeting (next) complex bound to RNA (substrate 2) | electron microscopy | A, E | — | — |
| 7Z4Z | Human NEXT dimer - focused reconstruction of the dimerization module | electron microscopy | B, D | — | 13 (best 0.61) |
| 7Z4Z | Human next dimer - focused reconstruction of the dimerization module | electron microscopy | B, D | — | 13 (best 0.61) |
| 7Z52 | Human next dimer - focused reconstruction of the single MTR4 | electron microscopy | B | ANP | 8 (best 0.84) |
| P42285 | AlphaFold monomer V2.0 prediction for exosome RNA helicase MTR4 (P42285) | — | — | — |
Ligands
Elsewhere
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