UniProt P41567
Eukaryotic translation initiation factor 1 (P41567)
Eukaryotic translation initiation factor 1 (UniProt P41567): 17 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P41567
- Protein
- Eukaryotic translation initiation factor 1
- Experimental structures
- 17
- Predicted models
- 1
- Pockets
- 2 · 2 records with a druggable one
Structures
18 records of P41567 in the MolNFT archive: 17 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2IF1 | Human translation initiation factor EIF1, NMR, 29 structures | solution nmr | A | — | — |
| 2IF1 | Human translation initiation factor EIF1, NMR, 29 structures | solution nmr | A | — | — |
| 4KZX | Rabbit 40S ribosomal subunit in complex with eIF1. | x-ray diffraction | l | — | — |
| 4KZX | Rabbit 40S ribosomal subunit in complex with EIF1. | x-ray diffraction | l | — | — |
| 4KZY | Rabbit 40S ribosomal subunit in complex with eIF1 and eIF1A. | x-ray diffraction | l | — | — |
| 4KZY | Rabbit 40S ribosomal subunit in complex with EIF1 and EIF1A. | x-ray diffraction | l | — | — |
| 6YBW | Structure of a human 48S translational initiation complex - 40S body | electron microscopy | p | — | — |
| 6YBW | Structure of a human 48S translational initiation complex - 40S body | electron microscopy | p | — | — |
| 6ZP4 | SARS-CoV-2 Nsp1 bound to a human 43S preinitiation ribosome complex - state 2 | electron microscopy | Z | — | 1 (best 0.83) |
| 6ZVJ | Structure of a human ABCE1-bound 43S pre-initiation complex - State II | electron microscopy | N | — | — |
| 7A09 | Structure of a human ABCE1-bound 43S pre-initiation complex - State III | electron microscopy | Z | — | — |
| 7QP6 | Structure of the human 48S initiation complex in open state (h48S AUG open) | electron microscopy | p | — | — |
| 8PJ1 | Structure of human 48S translation initiation complex in open codon scanning state (48S-1) | electron microscopy | p | — | — |
| 8PPK | Bat-Hp-CoV Nsp1 and eIF1 bound to the human 40S small ribosomal subunit | electron microscopy | p | — | — |
| 8PPL | MERS-CoV Nsp1 bound to the human 43S pre-initiation complex | electron microscopy | Ip | — | — |
| 8XXN | Cryo-EM structure of the human 43S ribosome with PDCD4 | electron microscopy | C1 | — | 1 (best 0.83) |
| 9BLN | The structure of human Pdcd4 bound to the 40S-eIF4A-eIF3-eIF1 complex | electron microscopy | W | — | — |
| P41567 | AlphaFold monomer V2.0 prediction for eukaryotic translation initiation factor 1 (P41567) | predicted | A | — | — |
Experiment against prediction
- 9BLN chain W against the predicted model P41567: TM-score 0.95, RMSD 0.77 Å
- 8PPK chain p against the predicted model P41567: TM-score 0.95, RMSD 0.90 Å
- 7QP6 chain p against the predicted model P41567: TM-score 0.92, RMSD 1.12 Å
- 6YBW chain p against the predicted model P41567: TM-score 0.90, RMSD 1.32 Å
- 6YBW chain p against the predicted model P41567: TM-score 0.90, RMSD 1.32 Å
- 8XXN chain C1 against the predicted model P41567: TM-score 0.87, RMSD 1.92 Å
- 4KZX chain l against the predicted model P41567: TM-score 0.84, RMSD 1.61 Å
- 4KZX chain l against the predicted model P41567: TM-score 0.84, RMSD 1.61 Å
- 6ZVJ chain N against the predicted model P41567: TM-score 0.83, RMSD 2.18 Å
- 4KZY chain l against the predicted model P41567: TM-score 0.81, RMSD 1.72 Å
Elsewhere
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