UniProt P41235
Hepatocyte nuclear factor 4-alpha (P41235)
Hepatocyte nuclear factor 4-alpha (UniProt P41235): 14 experimental structures on GenesisL1, 2 ligands bound, 20 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P41235
- Protein
- Hepatocyte nuclear factor 4-alpha
- Experimental structures
- 14
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 20 · 1 record with a druggable one
Structures
14 records of P41235 in the MolNFT archive: 14 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1PZL | Crystal structure of HNF4a LBD in complex with the ligand and the coactivator SRC-1 peptide | x-ray diffraction | A | — | — |
| 1PZL | Crystal structure of HNF4A lbd in complex with the ligand and the coactivator src-1 peptide | x-ray diffraction | A | — | — |
| 3CBB | Crystal Structure of Hepatocyte Nuclear Factor 4alpha in complex with DNA: Diabetes Gene Product | x-ray diffraction | A, B | — | — |
| 3CBB | Crystal structure of hepatocyte nuclear factor 4ALPHA in complex with DNA: diabetes gene product | x-ray diffraction | A, B | — | — |
| 3FS1 | Crystal structure of HNF4a LBD in complex with the ligand and the coactivator PGC-1a fragment | x-ray diffraction | A | — | — |
| 3FS1 | Crystal structure of HNF4A lbd in complex with the ligand and the coactivator pgc-1A fragment | x-ray diffraction | A | — | — |
| 4B7W | Ligand binding domain human hepatocyte nuclear factor 4alpha: Apo form | x-ray diffraction | A, B, C, D | — | — |
| 4B7W | Ligand binding domain human hepatocyte nuclear factor 4ALPHA: apo form | x-ray diffraction | A, B, C, D | — | — |
| 4IQR | Multi-Domain Organization of the HNF4alpha Nuclear Receptor Complex on DNA | x-ray diffraction | A, B, E, F | — | — |
| 4IQR | Multi-domain organization of the HNF4ALPHA nuclear receptor complex on DNA | x-ray diffraction | A, B, E, F | — | — |
| 6CHT | HNF4alpha in complex with the corepressor EBP1 fragment | x-ray diffraction | A, B, D, E, G, H, J, K, M, N, P, Q, S, T, V, W | DAO | 20 (best 0.88) |
| 6CHT | HNF4ALPHA in complex with the corepressor EBP1 fragment | x-ray diffraction | A, B, D, E, G, H, J, K, M, N, P, Q, S, T, V, W | DAO | — |
| 8C1L | Crystal structure of HNF4 alpha LBD in complexes with palmitic acid and GRIP-1 peptide | x-ray diffraction | A, B | PLM | — |
| P41235 | AlphaFold monomer V2.0 prediction for hepatocyte nuclear factor 4-alpha (P41235) | — | — | — |
Ligands
Elsewhere
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