UniProt P41227
N-alpha-acetyltransferase 10 (P41227)
N-alpha-acetyltransferase 10 (UniProt P41227), EC 2.3.1.255: 8 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 18 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P41227
- Protein
- N-alpha-acetyltransferase 10
- EC
- 2.3.1.255
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 18 · 4 records with a druggable one
Structures
9 records of P41227 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6C95 | The human nata (NAA10/NAA15) amino-terminal acetyltransferase complex bound to hypk | x-ray diffraction | B | ACE, IHP | — |
| 6C9M | The Human NatA (Naa10/Naa15) amino-terminal acetyltransferase complex | x-ray diffraction | B, D | IHP | — |
| 6C9M | The human nata (NAA10/NAA15) amino-terminal acetyltransferase complex | x-ray diffraction | B, D | ACE, IHP | — |
| 6PPL | Cryo-EM structure of human nate complex (NATA/NAA50) | electron microscopy | C | ACE, IHP, ACO | — |
| 6PW9 | Cryo-EM structure of human NatE/HYPK complex | electron microscopy | C | IHP, ACO | 9 (best 0.85) |
| 6PW9 | Cryo-EM structure of human NATE/HYPK complex | electron microscopy | C | ACE, IHP, ACO | — |
| 9FPZ | Human NatA-MAP2 80S ribosome complex | electron microscopy | 2 | — | 6 (best 0.80) |
| 9FQ0 | Human NatA-NAC-MAP1 80S ribosome complex | electron microscopy | 2 | IHP | 2 (best 0.82) |
| P41227 | AlphaFold monomer V2.0 prediction for N-alpha-acetyltransferase 10 (P41227) | predicted | A | — | 1 (best 0.65) |
Ligands
Experiment against prediction
- 6PPL chain C against the predicted model P41227: TM-score 0.98, RMSD 0.59 Å
- 9FPZ chain 2 against the predicted model P41227: TM-score 0.98, RMSD 0.69 Å
- 6C95 chain B against the predicted model P41227: TM-score 0.98, RMSD 0.73 Å
- 9FQ0 chain 2 against the predicted model P41227: TM-score 0.98, RMSD 0.77 Å
- 6PW9 chain C against the predicted model P41227: TM-score 0.97, RMSD 0.91 Å
- 6PW9 chain C against the predicted model P41227: TM-score 0.97, RMSD 0.91 Å
- 6C9M chain B against the predicted model P41227: TM-score 0.96, RMSD 1.10 Å
- 6C9M chain B against the predicted model P41227: TM-score 0.96, RMSD 1.10 Å
Elsewhere
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