UniProt P40969
Centromere DNA-binding protein complex CBF3 subunit B (P40969)
Centromere DNA-binding protein complex CBF3 subunit B (UniProt P40969): 20 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 39 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P40969
- Protein
- Centromere DNA-binding protein complex CBF3 subunit B
- Experimental structures
- 20
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 39 · 4 records with a druggable one
Structures
21 records of P40969 in the MolNFT archive: 20 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2QUQ | Crystal Structure of the Essential Inner Kinetochore Protein Cep3p | x-ray diffraction | A | — | — |
| 2QUQ | Crystal structure of the essential inner kinetochore protein CEP3P | x-ray diffraction | A | — | — |
| 2VEQ | Insights into kinetochore-DNA interactions from the structure of Cep3p | x-ray diffraction | A | — | — |
| 2VEQ | Insights into kinetochore-DNA interactions from the structure of CEP3P | x-ray diffraction | A | — | — |
| 6F07 | CBF3 Core Complex | electron microscopy | A, B | ZN | 20 (best 0.82) |
| 6F07 | CBF3 core complex | electron microscopy | A, B | ZN | — |
| 6FE8 | Cryo-EM structure of the core Centromere Binding Factor 3 complex | electron microscopy | A, B | — | 14 (best 0.83) |
| 6FE8 | Cryo-EM structure of the core centromere binding factor 3 complex | electron microscopy | A, B | — | — |
| 6GSA | Core Centromere Binding Factor 3 (CBF3) with monomeric Ndc10 | electron microscopy | A, B | — | — |
| 6GSA | Core centromere binding factor 3 (CBF3) with monomeric NDC10 | electron microscopy | A, B | — | — |
| 6GYP | Cryo-EM structure of the CBF3-core-Ndc10-DBD complex of the budding yeast kinetochore | electron microscopy | B, C | — | — |
| 6GYP | Cryo-EM structure of the CBF3-core-NDC10-dbd complex of the budding yeast kinetochore | electron microscopy | B, C | — | — |
| 6GYS | Cryo-EM structure of the CBF3-CEN3 complex of the budding yeast kinetochore | electron microscopy | B, C, I, J | ZN | — |
| 6GYS | Cryo-EM structure of the CBF3-CEN3 complex of the budding yeast kinetochore | electron microscopy | B, C, I, J | ZN | — |
| 6GYU | Cryo-EM structure of the CBF3-msk complex of the budding yeast kinetochore | electron microscopy | B, C | ZN | — |
| 6GYU | Cryo-EM structure of the CBF3-msk complex of the budding yeast kinetochore | electron microscopy | B, C | ZN | — |
| 7K79 | CBF3 | electron microscopy | L, O | — | — |
| 7K7G | nucleosome and Gal4 complex | electron microscopy | M | ZN | 1 (best 0.69) |
| 7K7G | Nucleosome and GAL4 complex | electron microscopy | M | ZN | — |
| 8OW1 | Cryo-EM structure of the yeast Inner kinetochore bound to a CENP-A nucleosome. | electron microscopy | ce, CE | — | 4 (best 0.83) |
| P40969 | AlphaFold monomer V2.0 prediction for centromere DNA-binding protein complex CBF3 subunit B (P40969) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 8 records
Experiment against prediction
- 2QUQ chain A against the predicted model P40969: TM-score 0.99, RMSD 0.70 Å
- 2QUQ chain A against the predicted model P40969: TM-score 0.99, RMSD 0.70 Å
- 2VEQ chain A against the predicted model P40969: TM-score 0.99, RMSD 0.93 Å
- 2VEQ chain A against the predicted model P40969: TM-score 0.99, RMSD 0.93 Å
- 6FE8 chain B against the predicted model P40969: TM-score 0.99, RMSD 0.77 Å
- 6FE8 chain B against the predicted model P40969: TM-score 0.99, RMSD 0.77 Å
- 6GSA chain B against the predicted model P40969: TM-score 0.99, RMSD 0.77 Å
- 6GSA chain B against the predicted model P40969: TM-score 0.99, RMSD 0.77 Å
- 6GYU chain C against the predicted model P40969: TM-score 0.99, RMSD 0.68 Å
- 6GYU chain C against the predicted model P40969: TM-score 0.99, RMSD 0.68 Å
Elsewhere
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