UniProt P40925
Malate dehydrogenase, cytoplasmic (P40925)
Malate dehydrogenase, cytoplasmic (UniProt P40925), EC 1.1.1.37, 1.1.1.96: 4 experimental structures and 1 predicted model on GenesisL1, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P40925
- Protein
- Malate dehydrogenase, cytoplasmic
- EC
- 1.1.1.37, 1.1.1.96
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 7 · 1 record with a druggable one
Structures
5 records of P40925 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7RM9 | Human Malate Dehydrogenase I (MDHI) | x-ray diffraction | A, B | — | — |
| 7RM9 | Human malate dehydrogenase I (mdhi) | x-ray diffraction | A, B | — | — |
| 7RRL | Alternate Crystal Form of Human Malate Dehydrogenase I | x-ray diffraction | A, B | — | 7 (best 0.67) |
| 7RRL | Alternate crystal form of human malate dehydrogenase I | x-ray diffraction | A, B | — | — |
| P40925 | AlphaFold monomer V2.0 prediction for malate dehydrogenase, cytoplasmic (P40925) | predicted | A | — | — |
Experiment against prediction
- 7RRL chain A against the predicted model P40925: TM-score 1.00, RMSD 0.44 Å
- 7RRL chain A against the predicted model P40925: TM-score 1.00, RMSD 0.44 Å
- 7RM9 chain B against the predicted model P40925: TM-score 0.99, RMSD 0.49 Å
- 7RM9 chain B against the predicted model P40925: TM-score 0.99, RMSD 0.49 Å
- 7RRL chain B against the predicted model P40925: TM-score 0.99, RMSD 0.69 Å
- 7RRL chain B against the predicted model P40925: TM-score 0.99, RMSD 0.69 Å
- 7RM9 chain A against the predicted model P40925: TM-score 0.98, RMSD 1.25 Å
- 7RM9 chain A against the predicted model P40925: TM-score 0.98, RMSD 1.25 Å
Elsewhere
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